AMPA Receptor Antagonists Facilitate NEDD4-2-Mediated GRIA1 Ubiquitination by Regulating PP2B-ERK1/2-SGK1 Pathway in Chronic Epilepsy Rats

The neural precursor cell expressed by developmentally downregulated gene 4-2 (NEDD4-2) is a ubiquitin E3 ligase that has a high affinity toward binding and ubiquitinating glutamate ionotropic receptor α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) type subunit 1 (GRIA1, also referred t...

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Detalles Bibliográficos
Autores principales: Kim, Ji-Eun, Lee, Duk-Shin, Park, Hana, Kim, Tae-Hyun, Kang, Tae-Cheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391511/
https://www.ncbi.nlm.nih.gov/pubmed/34440273
http://dx.doi.org/10.3390/biomedicines9081069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391511/
https://www.ncbi.nlm.nih.gov/pubmed/34440273
http://dx.doi.org/10.3390/biomedicines9081069

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