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Increased Hypothalamic Anti-Inflammatory Mediators in Non-Diabetic Insulin Receptor Substrate 2-Deficient Mice

Insulin receptor substrate (IRS) 2 is a key mediator of insulin signaling and IRS-2 knockout (IRS2(−/−)) mice are a preclinical model to study the development of diabetes, as they develop peripheral insulin resistance and beta-cell failure. The differential inflammatory profile and insulin signaling...

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Detalles Bibliográficos
Autores principales:	Vinaixa, María, Canelles, Sandra, González-Murillo, África, Ferreira, Vítor, Grajales, Diana, Guerra-Cantera, Santiago, Campillo-Calatayud, Ana, Ramírez-Orellana, Manuel, Yanes, Óscar, Frago, Laura M., Valverde, Ángela M., Barrios, Vicente
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391514/ https://www.ncbi.nlm.nih.gov/pubmed/34440853 http://dx.doi.org/10.3390/cells10082085

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