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Stabilization Effect of Intrinsically Disordered Regions on Multidomain Proteins: The Case of the Methyl-CpG Protein 2, MeCP2

Intrinsic disorder plays an important functional role in proteins. Disordered regions are linked to posttranslational modifications, conformational switching, extra/intracellular trafficking, and allosteric control, among other phenomena. Disorder provides proteins with enhanced plasticity, resultin...

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Detalles Bibliográficos
Autores principales: Ortega-Alarcon, David, Claveria-Gimeno, Rafael, Vega, Sonia, Jorge-Torres, Olga C., Esteller, Manel, Abian, Olga, Velazquez-Campoy, Adrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391517/
https://www.ncbi.nlm.nih.gov/pubmed/34439881
http://dx.doi.org/10.3390/biom11081216