Antithetic hTERT Regulation by Androgens in Prostate Cancer Cells: hTERT Inhibition Is Mediated by the ING1 and ING2 Tumor Suppressors

SIMPLE SUMMARY: The expression of the catalytic subunit of the human telomerase reverse transcriptase subunit (hTERT) is hormonally controlled. Androgen treatment suppresses the hTERT expression at a transcriptional level in prostate cancer cells. Here, we identified the responsive promoter element...

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Detalles Bibliográficos
Autores principales: Bartsch, Sophie, Mirzakhani, Kimia, Neubert, Laura, Stenzel, Alexander, Ehsani, Marzieh, Esmaeili, Mohsen, Pungsrinont, Thanakorn, Kacal, Merve, Rasa, Seyed Mohammad Mahdi, Kallenbach, Julia, Damodaran, Divya, Ribaudo, Federico, Grimm, Marc-Oliver, Neri, Francesco, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391603/
https://www.ncbi.nlm.nih.gov/pubmed/34439179
http://dx.doi.org/10.3390/cancers13164025

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