The Unfolded Protein Response Is a Major Driver of LCN2 Expression in BCR–ABL- and JAK2V617F-Positive MPN

SIMPLE SUMMARY: Lipocalin 2 (LCN2) is a proinflammatory mediator increased in the blood of patients with myeloproliferative neoplasms (MPN) and other hematologic malignancies, significantly contributing to MPN disease initiation and progression. Here, we investigated the underlying mechanisms of LCN...

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Detalles Bibliográficos
Autores principales: Tillmann, Stefan, Olschok, Kathrin, Schröder, Sarah K., Bütow, Marlena, Baumeister, Julian, Kalmer, Milena, Preußger, Vera, Weinbergerova, Barbora, Kricheldorf, Kim, Mayer, Jiri, Kubesova, Blanka, Racil, Zdenek, Wessiepe, Martina, Eschweiler, Jörg, Isfort, Susanne, Brümmendorf, Tim H., Becker, Walter, Schemionek, Mirle, Weiskirchen, Ralf, Koschmieder, Steffen, Chatain, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391615/
https://www.ncbi.nlm.nih.gov/pubmed/34439364
http://dx.doi.org/10.3390/cancers13164210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391615/
https://www.ncbi.nlm.nih.gov/pubmed/34439364
http://dx.doi.org/10.3390/cancers13164210

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