Pathophysiological and Pharmacological Characteristics of KCNJ5 157-159delITE Somatic Mutation in Aldosterone-Producing Adenomas

Mutated channelopathy could play important roles in the pathogenesis of aldosterone-producing adenoma (APA). In this study, we identified a somatic mutation, KCNJ5 157-159delITE, and reported its immunohistological, pathophysiological and pharmacological characteristics. We conducted patch-clamp exp...

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Detalles Bibliográficos
Autores principales: Peng, Kang-Yung, Liao, Hung-Wei, Chueh, Jeff S., Pan, Chien-Yuan, Lin, Yen-Hung, Chen, Yung-Ming, Chen, Peng-Ying, Huang, Chun-Lin, Wu, Vin-Cent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391641/
https://www.ncbi.nlm.nih.gov/pubmed/34440230
http://dx.doi.org/10.3390/biomedicines9081026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391641/
https://www.ncbi.nlm.nih.gov/pubmed/34440230
http://dx.doi.org/10.3390/biomedicines9081026

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