Development and Validation of a Long-Term 3D Glioblastoma Cell Culture in Alginate Microfibers as a Novel Bio-Mimicking Model System for Preclinical Drug Testing

Background: Various three-dimensional (3D) glioblastoma cell culture models have a limited duration of viability. Our aim was to develop a long-term 3D glioblastoma model, which is necessary for reliable drug response studies. Methods: Human U87 glioblastoma cells were cultured in alginate microfibe...

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Detalles Bibliográficos
Autores principales: Dragoj, Miodrag, Stojkovska, Jasmina, Stanković, Tijana, Dinić, Jelena, Podolski-Renić, Ana, Obradović, Bojana, Pešić, Milica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391761/
https://www.ncbi.nlm.nih.gov/pubmed/34439644
http://dx.doi.org/10.3390/brainsci11081025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391761/
https://www.ncbi.nlm.nih.gov/pubmed/34439644
http://dx.doi.org/10.3390/brainsci11081025

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