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Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy

SIMPLE SUMMARY: Cancerous cells acquire genetic mutations that can lead to changes in the amino acid sequence of proteins. These altered amino acid sequences, or “neoantigens” allow the immune system to recognize the mutated cells as “non-self” and eliminate them. This review outlines discoveries th...

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Detalles Bibliográficos
Autores principales: Verdon, Daniel J., Jenkins, Misty R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391927/
https://www.ncbi.nlm.nih.gov/pubmed/34439399
http://dx.doi.org/10.3390/cancers13164245