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Identification and Targeting of Mutant Peptide Neoantigens in Cancer Immunotherapy
SIMPLE SUMMARY: Cancerous cells acquire genetic mutations that can lead to changes in the amino acid sequence of proteins. These altered amino acid sequences, or “neoantigens” allow the immune system to recognize the mutated cells as “non-self” and eliminate them. This review outlines discoveries th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391927/ https://www.ncbi.nlm.nih.gov/pubmed/34439399 http://dx.doi.org/10.3390/cancers13164245 |