In Uveal Melanoma, Angiopoietin-2 but Not Angiopoietin-1 Is Increased in High-Risk Tumors, Providing a Potential Druggable Target

SIMPLE SUMMARY: We hypothesize that proangiogenic factors such as angiopoietin-1 (ANG-1) and angiopoietin-2 (ANG-2), two targetable cytokines, may play a role in tumor development in uveal melanoma. We determined the expression of these cytokines in both uveal melanoma tissue as well as in aqueous h...

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Detalles Bibliográficos
Autores principales: ten Voorde, Anna M.W., Wierenga, Annemijn P.A., Nell, Rogier J., van der Velden, Pieter A., Luyten, Gregorius P.M., Verdijk, Robert M., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391938/
https://www.ncbi.nlm.nih.gov/pubmed/34439141
http://dx.doi.org/10.3390/cancers13163986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391938/
https://www.ncbi.nlm.nih.gov/pubmed/34439141
http://dx.doi.org/10.3390/cancers13163986

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