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Cystatin C Deficiency Increases LPS-Induced Sepsis and NLRP3 Inflammasome Activation in Mice
Cystatin C is a potent cysteine protease inhibitor that plays an important role in various biological processes including cancer, cardiovascular diseases and neurodegenerative diseases. However, the role of CstC in inflammation is still unclear. In this study we demonstrated that cystatin C-deficien...
Autores principales: | Biasizzo, Monika, Trstenjak-Prebanda, Mojca, Dolinar, Klemen, Pirkmajer, Sergej, Završnik, Janja, Turk, Boris, Kopitar-Jerala, Nataša |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8391971/ https://www.ncbi.nlm.nih.gov/pubmed/34440840 http://dx.doi.org/10.3390/cells10082071 |
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