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Metformin and Cancer Glucose Metabolism: At the Bench or at the Bedside?

Several studies reported that metformin, the most widely used drug for type 2 diabetes, might affect cancer aggressiveness. The biguanide seems to directly impair cancer energy asset, with the consequent phosphorylation of AMP-activated protein kinase (AMPK) inhibiting cell proliferation and tumor g...

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Detalles Bibliográficos
Autores principales:	Marini, Cecilia, Cossu, Vanessa, Bauckneht, Matteo, Lanfranchi, Francesco, Raffa, Stefano, Orengo, Anna Maria, Ravera, Silvia, Bruno, Silvia, Sambuceti, Gianmario
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392176/ https://www.ncbi.nlm.nih.gov/pubmed/34439897 http://dx.doi.org/10.3390/biom11081231

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