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PI3K/Akt Pathway: The Indestructible Role of a Vintage Target as a Support to the Most Recent Immunotherapeutic Approaches

SIMPLE SUMMARY: PI3K/Akt pathway has an impressive story as tumor marker. PI3K-dependent solid tumors have been studied for several years in order to inhibit the pathway at different levels along the signaling. Despite the highly satisfactory results obtained in vitro and in xenograft mouse tumor mo...

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Detalles Bibliográficos
Autores principales: Caforio, Matteo, de Billy, Emmanuel, De Angelis, Biagio, Iacovelli, Stefano, Quintarelli, Concetta, Paganelli, Valeria, Folgiero, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392360/
https://www.ncbi.nlm.nih.gov/pubmed/34439194
http://dx.doi.org/10.3390/cancers13164040