Cargando…

The Link between VAPB Loss of Function and Amyotrophic Lateral Sclerosis

The VAP proteins are integral adaptor proteins of the endoplasmic reticulum (ER) membrane that recruit a myriad of interacting partners to the ER surface. Through these interactions, the VAPs mediate a large number of processes, notably the generation of membrane contact sites between the ER and ess...

Descripción completa

Detalles Bibliográficos
Autores principales:	Borgese, Nica, Iacomino, Nicola, Colombo, Sara Francesca, Navone, Francesca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392409/ https://www.ncbi.nlm.nih.gov/pubmed/34440634 http://dx.doi.org/10.3390/cells10081865

Ejemplares similares

Mutant VAPB: Culprit or Innocent Bystander of Amyotrophic Lateral Sclerosis?
por: Borgese, Nica, et al.
Publicado: (2021)

Amyotrophic Lateral Sclerosis-Linked Mutant VAPB Inclusions Do Not Interfere with Protein Degradation Pathways or Intracellular Transport in a Cultured Cell Model
por: Genevini, Paola, et al.
Publicado: (2014)

Characterization of the Properties of a Novel Mutation in VAPB in Familial Amyotrophic Lateral Sclerosis
por: Chen, Han-Jou, et al.
Publicado: (2010)

Autophagy and Neurodegeneration: Insights from a Cultured Cell Model of ALS
por: Navone, Francesca, et al.
Publicado: (2015)

A genetic screen identifies Tor as an interactor of VAPB in a Drosophila model of amyotrophic lateral sclerosis
por: Deivasigamani, Senthilkumar, et al.
Publicado: (2014)

Amyotrophic lateral sclerosis (ALS)-associated VAPB-P56S inclusions represent an ER quality control compartment
por: Kuijpers, Marijn, et al.
Publicado: (2013)

Disruption of the VAPB-PTPIP51 ER-mitochondria tethering proteins in post-mortem human amyotrophic lateral sclerosis
por: Hartopp, Naomi, et al.
Publicado: (2022)

The links between diabetes mellitus and amyotrophic lateral sclerosis
por: Vasta, Rosario, et al.
Publicado: (2021)

Genetics and Sex in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS): Is There a Link?
por: Trojsi, Francesca, et al.
Publicado: (2020)

Is SOD1 loss of function involved in amyotrophic lateral sclerosis?
por: Saccon, Rachele A., et al.
Publicado: (2013)

Yeast Models of Amyotrophic Lateral Sclerosis Type 8 Mimic Phenotypes Seen in Mammalian Cells Expressing Mutant VAPB(P56S)
por: Stump, AnnaMari L., et al.
Publicado: (2023)

Amyotrophic lateral sclerosis
por: Wijesekera, Lokesh C, et al.
Publicado: (2009)

Dihydrotestosterone in Amyotrophic lateral sclerosis—The missing link?
por: Sawal, Nishit, et al.
Publicado: (2020)

Dysautonomia in Amyotrophic Lateral Sclerosis
por: Oprisan, Alexandra L., et al.
Publicado: (2023)

Prionoids in amyotrophic lateral sclerosis
por: Gosset, Philippe, et al.
Publicado: (2022)

Loss of TDP-43 function contributes to genomic instability in amyotrophic lateral sclerosis
por: Fang, Minggang, et al.
Publicado: (2023)

The tale of tail-anchored proteins: coming from the cytosol and looking for a membrane
por: Borgese, Nica, et al.
Publicado: (2003)

Enteroviral Infection: The Forgotten Link to Amyotrophic Lateral Sclerosis?
por: Xue, Yuan Chao, et al.
Publicado: (2018)

Diverse roles of FUS in Amyotrophic Lateral Sclerosis
por: Carri, Maria Teresa, et al.
Publicado: (2015)

Functional Loss and Mortality in Randomized Clinical Trials for Amyotrophic Lateral Sclerosis: To Combine, or Not to Combine—That is the Estimand
por: van Eijk, Ruben P.A., et al.
Publicado: (2022)

The Key Role of Astrocytes in Amyotrophic Lateral Sclerosis and Their Commitment to Glutamate Excitotoxicity
por: Provenzano, Francesca, et al.
Publicado: (2023)

Functional Biomarkers for Amyotrophic Lateral Sclerosis
por: Huynh, William, et al.
Publicado: (2019)

Genetics of amyotrophic lateral sclerosis: an update
por: Chen, Sheng, et al.
Publicado: (2013)

Protein aggregation in amyotrophic lateral sclerosis
por: Blokhuis, Anna M., et al.
Publicado: (2013)

Risk factors for amyotrophic lateral sclerosis
por: Ingre, Caroline, et al.
Publicado: (2015)

Neuroimaging Endpoints in Amyotrophic Lateral Sclerosis
por: Menke, Ricarda A. L., et al.
Publicado: (2016)

Amyotrophic lateral sclerosis as a synaptopathy
por: Fogarty, Matthew J.
Publicado: (2019)

What causes amyotrophic lateral sclerosis?
por: Martin, Sarah, et al.
Publicado: (2017)

Gene Therapy in Amyotrophic Lateral Sclerosis
por: Fang, Ton, et al.
Publicado: (2022)

Sensory Involvement in Amyotrophic Lateral Sclerosis
por: Rubio, Miguel A., et al.
Publicado: (2022)

Extracellular Vesicles in Amyotrophic Lateral Sclerosis
por: McCluskey, Gavin, et al.
Publicado: (2022)

Correlation between clinical phenotype and electromyographic parameters in amyotrophic lateral sclerosis
por: Colombo, Eleonora, et al.
Publicado: (2022)

Is there a link between amyotrophic lateral sclerosis and treatment with TNF-alpha inhibitors?
por: Börjesson, A., et al.
Publicado: (2013)

Genome-wide genetic links between amyotrophic lateral sclerosis and autoimmune diseases
por: Li, Chun Yu, et al.
Publicado: (2021)

A comprehensive review of amyotrophic lateral sclerosis
por: Zarei, Sara, et al.
Publicado: (2015)

Mechanisms of Loss of Functions of Human Angiogenin Variants Implicated in Amyotrophic Lateral Sclerosis
por: Padhi, Aditya K., et al.
Publicado: (2012)

Glial Cells in Amyotrophic Lateral Sclerosis
por: Lasiene, Jurate, et al.
Publicado: (2011)

Redox Regulation in Amyotrophic Lateral Sclerosis
por: Parakh, Sonam, et al.
Publicado: (2013)

Amyotrophic lateral sclerosis mimic syndromes
por: Ghasemi, Majid
Publicado: (2016)

An overview on amyotrophic lateral sclerosis and cadmium
por: Oggiano, Riccardo, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_t9mr10e3e9qst7fhg8imc19q2d