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Investigating the Interplay between Myeloma Cells and Bone Marrow Stromal Cells in the Development of Drug Resistance: Dissecting the Role of Epigenetic Modifications

SIMPLE SUMMARY: Despite advances made in the last two decades, multiple myeloma (MM) is still an incurable disease. The genetic complexity of MM and the presence of intra-clonal heterogeneity are major contributors to disease relapse and the development of treatment resistance. Additionally, the bon...

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Detalles Bibliográficos
Autores principales: Schütt, Jacqueline, Nägler, Theresa, Schenk, Tino, Brioli, Annamaria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392438/
https://www.ncbi.nlm.nih.gov/pubmed/34439223
http://dx.doi.org/10.3390/cancers13164069