Cargando…

Transcriptomic Profiling Reveals Novel Candidate Genes and Signalling Programs in Breast Cancer Quiescence and Dormancy †

SIMPLE SUMMARY: Breast cancer can return many years after treatment of the primary tumour. This is caused by cells that have spread to other parts of the body and entered a non-dividing state called quiescence or dormancy that can last for decades. Dormant cancer cells are not sensitive to conventio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Quayle, Lewis A., Spicer, Amy, Ottewell, Penelope D., Holen, Ingunn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392441/ https://www.ncbi.nlm.nih.gov/pubmed/34439077 http://dx.doi.org/10.3390/cancers13163922

Ejemplares similares

Chemotherapy resistance and stemness in mitotically quiescent human breast cancer cells identified by fluorescent dye retention
por: Quayle, Lewis A., et al.
Publicado: (2018)

The differential anti-tumour effects of zoledronic acid in breast cancer – evidence for a role of the activin signaling pathway
por: Wilson, Caroline, et al.
Publicado: (2015)

The kinetochore protein Cenp-F is a potential novel target for zoledronic acid in breast cancer cells
por: Brown, Hannah K, et al.
Publicado: (2011)

IL-1 drives breast cancer growth and bone metastasis in vivo
por: Holen, Ingunn, et al.
Publicado: (2016)

The bone metastasis niche in breast cancer-potential overlap with the haematopoietic stem cell niche in vivo
por: Allocca, Gloria, et al.
Publicado: (2019)

Analysis of Dormancy-Associated Transcriptional Networks Reveals a Shared Quiescence Signature in Lung and Colorectal Cancer
por: Cuccu, Adriano, et al.
Publicado: (2022)

Diapause and quiescence: dormancy mechanisms that contribute to the geographical expansion of mosquitoes and their evolutionary success
por: Diniz, Diego Felipe Araujo, et al.
Publicado: (2017)

Osteoblast-Derived Paracrine and Juxtacrine Signals Protect Disseminated Breast Cancer Cells from Stress
por: Hughes, Russell, et al.
Publicado: (2021)

Loss of plakoglobin promotes decreased cell-cell contact, increased invasion, and breast cancer cell dissemination in vivo
por: Holen, Ingunn, et al.
Publicado: (2012)

Parathyroid Hormone (PTH) Increases Skeletal Tumour Growth and Alters Tumour Distribution in an In Vivo Model of Breast Cancer
por: Brown, Hannah K., et al.
Publicado: (2018)

Erratum to: Loss of plakoglobin promotes cell-cell contact, increased invasion and breast cancer cell dissemination in vivo
por: Holen, Ingunn, et al.
Publicado: (2017)

Epigenetic and Transcriptomic Programming of HSC Quiescence Signaling in Large for Gestational Age Neonates
por: Pelletier, Alexandre, et al.
Publicado: (2022)

NR2F1 controls tumor cell dormancy via SOX9 and RARβ driven quiescence programs
por: Sosa, Maria Soledad, et al.
Publicado: (2015)

The CDK4/6 Inhibitor Palbociclib Inhibits Estrogen-Positive and Triple Negative Breast Cancer Bone Metastasis In Vivo
por: Saleh, Lubaid, et al.
Publicado: (2023)

Transcriptome Profiles Reveal the Crucial Roles of Hormone and Sugar in the Bud Dormancy of Prunus mume
por: Zhang, Zhiyong, et al.
Publicado: (2018)

Short day transcriptomic programming during induction of dormancy in grapevine
por: Fennell, Anne Y., et al.
Publicado: (2015)

Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts
por: Lefley, Diane, et al.
Publicado: (2019)

The frequency of osteolytic bone metastasis is determined by conditions of the soil, not the number of seeds; evidence from in vivo models of breast and prostate cancer
por: Wang, Ning, et al.
Publicado: (2015)

Integrated Analysis of the Transcriptome and Metabolome Revealed Candidate Genes Involved in GA(3)-Induced Dormancy Release in Leymus chinensis Seeds
por: Li, Bing, et al.
Publicado: (2021)

Pretreatment of breast cancer cells with doxorubicin facilitates the subsequent uptake of zoledronic acid
por: Lefley, DV, et al.
Publicado: (2008)

Mechanisms of apoptosis and cell-cycle arrest in subcutaneous breast tumours treated sequentially with doxorubicin followed by zoledronic acid
por: Ottewell, PD, et al.
Publicado: (2008)

Transcriptome analysis and metabolic profiling reveal the key role of α-linolenic acid in dormancy regulation of European pear
por: Gabay, Gilad, et al.
Publicado: (2019)

Transcriptome profiles revealed molecular mechanisms of alternating temperatures in breaking the epicotyl morphophysiological dormancy of Polygonatum sibiricum seeds
por: Liao, Dengqun, et al.
Publicado: (2021)

Melanoma dormancy in a mouse model is linked to GILZ/FOXO3A-dependent quiescence of disseminated stem-like cells
por: Touil, Yasmine, et al.
Publicado: (2016)

Anti-tumour activity of bisphosphonates in preclinical models of breast cancer
por: Holen, Ingunn, et al.
Publicado: (2010)

The role of IL-1B in breast cancer bone metastasis
por: Tulotta, Claudia, et al.
Publicado: (2018)

A Transcriptional Program Mediating Entry into Cellular Quiescence
por: Liu, Helen, et al.
Publicado: (2007)

Dormant cancer cells: programmed quiescence, senescence, or both?
por: Truskowski, Kevin, et al.
Publicado: (2023)

How fall dormancy benefits alfalfa winter-survival? Physiologic and transcriptomic analyses of dormancy process
por: Liu, Zhi-Ying, et al.
Publicado: (2019)

The transcriptomic and epigenetic map of vascular quiescence in the continuous lung endothelium
por: Schlereth, Katharina, et al.
Publicado: (2018)

CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment
por: Westbrook, Jules A., et al.
Publicado: (2016)

Transcriptome profiling provides insights into dormancy release during cold storage of Lilium pumilum
por: Wang, Wang, et al.
Publicado: (2018)

Transcriptome and Metabolite Conjoint Analysis Reveals the Seed Dormancy Release Process in Callery Pear
por: Zhang, Jing, et al.
Publicado: (2022)

CDK4/6 inhibitors: A potential therapeutic approach for triple negative breast cancer
por: Saleh, Lubaid, et al.
Publicado: (2021)

Atomic force microscopy reveals the mechanical properties of breast cancer bone metastases
por: Chen, Xinyue, et al.
Publicado: (2021)

IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer
por: Tulotta, Claudia, et al.
Publicado: (2021)

The bone microenvironment - Multiple players involved in cancer progression
por: Holen, Ingunn
Publicado: (2016)

Tumour dormancy in breast cancer: an update
por: Brackstone, Muriel, et al.
Publicado: (2007)

In vivo models in breast cancer research: progress, challenges and future directions
por: Holen, Ingunn, et al.
Publicado: (2017)

A role for CBFβ in maintaining the metastatic phenotype of breast cancer cells
por: Ran, Ran, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_pvoblt2dsrd4i4cr02lql0qfch