Applying Bioinformatic Platforms, In Vitro, and In Vivo Functional Assays in the Characterization of Genetic Variants in the GH/IGF Pathway Affecting Growth and Development

Heritability accounts for over 80% of adult human height, indicating that genetic variability is the main determinant of stature. The rapid technological development of Next-Generation Sequencing (NGS), particularly Whole Exome Sequencing (WES), has resulted in the characterization of several geneti...

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Detalles Bibliográficos
Autores principales: Domené, Sabina, Scaglia, Paula A., Gutiérrez, Mariana L., Domené, Horacio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392544/
https://www.ncbi.nlm.nih.gov/pubmed/34440832
http://dx.doi.org/10.3390/cells10082063

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