Cargando…
Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center
The shock index (SI) is a useful tool for predicting the injury severity and mortality in patients with trauma. However, pediatric physiology differs from that of adults. In the pediatric trauma population, the shock status may be obscured within the normal range of vital signs. Pediatric age-adjust...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392594/ https://www.ncbi.nlm.nih.gov/pubmed/34438579 http://dx.doi.org/10.3390/children8080688 |
_version_ | 1783743540103217152 |
---|---|
author | Yang, Ya-Chih Hsieh, Tsung-Han Liu, Chi-Yuan Chang, Chun-Yu Hou, Yueh-Tseng Lin, Po-Chen Chen, Yu-Long Chien, Da-Sen Yiang, Giou-Teng Wu, Meng-Yu |
author_facet | Yang, Ya-Chih Hsieh, Tsung-Han Liu, Chi-Yuan Chang, Chun-Yu Hou, Yueh-Tseng Lin, Po-Chen Chen, Yu-Long Chien, Da-Sen Yiang, Giou-Teng Wu, Meng-Yu |
author_sort | Yang, Ya-Chih |
collection | PubMed |
description | The shock index (SI) is a useful tool for predicting the injury severity and mortality in patients with trauma. However, pediatric physiology differs from that of adults. In the pediatric trauma population, the shock status may be obscured within the normal range of vital signs. Pediatric age-adjusted SI (SIPA) is reported more accurately compared to SI. In our study, we conducted a 10 year retrospective cohort study of pediatric trauma population to evaluate the SI and SIPA in predicting mortality, intensive care unit (ICU) admission, and the need for surgery. This retrospective cohort study included 1265 pediatric trauma patients from January 2009 to June 2019 at the Taipei Tzu Chi Hospital, who had a history of hospitalization. The primary outcome of this investigation was in-hospital mortality, and the secondary outcomes were the length of hospital and ICU stay, operation times, and ICU admission times. The SIPA group can detect changes in vital signs early to reflect shock progression. In the elevated SIPA group, more severe traumatic injuries were identified, including high injury severity score (ISS), revised trauma score (RTS), and new injury severity score (NISS) scores than SI > 0.9. The odds ratio of elevated SIPA and SI (>0.9) to predict ISS ≥ 16 was 3.593 (95% Confidence interval [CI]: 2.175–5.935, p < 0.001) and 2.329 (95% CI: 1.454–3.730, p < 0.001). SI and SIPA are useful for identifying the compensatory phase of shock in prehospital and hospital settings, especially in corresponding normal to low-normal blood pressure. SIPA is effective in predicting the mortality and severity of traumatic injuries in the pediatric population. However, SI and SIPA were not significant predictors of ICU admission and the need for surgery analysis. |
format | Online Article Text |
id | pubmed-8392594 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83925942021-08-28 Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center Yang, Ya-Chih Hsieh, Tsung-Han Liu, Chi-Yuan Chang, Chun-Yu Hou, Yueh-Tseng Lin, Po-Chen Chen, Yu-Long Chien, Da-Sen Yiang, Giou-Teng Wu, Meng-Yu Children (Basel) Article The shock index (SI) is a useful tool for predicting the injury severity and mortality in patients with trauma. However, pediatric physiology differs from that of adults. In the pediatric trauma population, the shock status may be obscured within the normal range of vital signs. Pediatric age-adjusted SI (SIPA) is reported more accurately compared to SI. In our study, we conducted a 10 year retrospective cohort study of pediatric trauma population to evaluate the SI and SIPA in predicting mortality, intensive care unit (ICU) admission, and the need for surgery. This retrospective cohort study included 1265 pediatric trauma patients from January 2009 to June 2019 at the Taipei Tzu Chi Hospital, who had a history of hospitalization. The primary outcome of this investigation was in-hospital mortality, and the secondary outcomes were the length of hospital and ICU stay, operation times, and ICU admission times. The SIPA group can detect changes in vital signs early to reflect shock progression. In the elevated SIPA group, more severe traumatic injuries were identified, including high injury severity score (ISS), revised trauma score (RTS), and new injury severity score (NISS) scores than SI > 0.9. The odds ratio of elevated SIPA and SI (>0.9) to predict ISS ≥ 16 was 3.593 (95% Confidence interval [CI]: 2.175–5.935, p < 0.001) and 2.329 (95% CI: 1.454–3.730, p < 0.001). SI and SIPA are useful for identifying the compensatory phase of shock in prehospital and hospital settings, especially in corresponding normal to low-normal blood pressure. SIPA is effective in predicting the mortality and severity of traumatic injuries in the pediatric population. However, SI and SIPA were not significant predictors of ICU admission and the need for surgery analysis. MDPI 2021-08-10 /pmc/articles/PMC8392594/ /pubmed/34438579 http://dx.doi.org/10.3390/children8080688 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yang, Ya-Chih Hsieh, Tsung-Han Liu, Chi-Yuan Chang, Chun-Yu Hou, Yueh-Tseng Lin, Po-Chen Chen, Yu-Long Chien, Da-Sen Yiang, Giou-Teng Wu, Meng-Yu Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center |
title | Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center |
title_full | Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center |
title_fullStr | Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center |
title_full_unstemmed | Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center |
title_short | Analysis of Clinical Outcome and Predictors of Mortality in Pediatric Trauma Population: Evidence from a 10 Year Analysis in a Single Center |
title_sort | analysis of clinical outcome and predictors of mortality in pediatric trauma population: evidence from a 10 year analysis in a single center |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392594/ https://www.ncbi.nlm.nih.gov/pubmed/34438579 http://dx.doi.org/10.3390/children8080688 |
work_keys_str_mv | AT yangyachih analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT hsiehtsunghan analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT liuchiyuan analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT changchunyu analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT houyuehtseng analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT linpochen analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT chenyulong analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT chiendasen analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT yianggiouteng analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter AT wumengyu analysisofclinicaloutcomeandpredictorsofmortalityinpediatrictraumapopulationevidencefroma10yearanalysisinasinglecenter |