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The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study
(1) Background: This study compared anterior attentional–intentional system performance between three groups: Parkinson’s disease (PD) patients with normal cognition (PD-NC), with mild cognitive impairment (PD-MCI), and a comparison group (CG). It also evaluated the feasibility of the recruitment an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392698/ https://www.ncbi.nlm.nih.gov/pubmed/34439632 http://dx.doi.org/10.3390/brainsci11081013 |
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author | Golińska, Paulina Beata Sawicki, Artur Józef Bieleninik, Łucja Bidzan, Mariola |
author_facet | Golińska, Paulina Beata Sawicki, Artur Józef Bieleninik, Łucja Bidzan, Mariola |
author_sort | Golińska, Paulina Beata |
collection | PubMed |
description | (1) Background: This study compared anterior attentional–intentional system performance between three groups: Parkinson’s disease (PD) patients with normal cognition (PD-NC), with mild cognitive impairment (PD-MCI), and a comparison group (CG). It also evaluated the feasibility of the recruitment and study procedures; (2) Methods: From 45 participants recruited, 39 were allocated (mean age 65.31; 43.59% men) to PD-NC, PD-MCI and CG (13 per group). To assess attention, we used three tasks from the ROtman–Baycrest Battery for Investigating Attention: Simple Reaction time (RT), Choice RT, and Prepare RT. We conducted a mixed-model analysis of variance with a 3 (groups) × 4 (tasks) design to compare reaction times; (3) Results: PD-MCI had slower reaction times than PD-NC (p = 0.028) and the CG (p = 0.052); there was no difference between PD-NC and CG. PD-MCI might perform worse on monitoring tasks than PD-NC, Z = −1.68, p = 0.092. Nearly half the volunteers from the CG and 87% of all eligible patients were enrolled in the study and completed all neuropsychological procedures; (4) Conclusions: General cognitive decline appears related to partial deficits in energization and tends to impair attentional monitoring. Furthermore, PD-NC exhibited similar reaction times to the CG. Results from the feasibility study contributed to the definitive study. |
format | Online Article Text |
id | pubmed-8392698 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83926982021-08-28 The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study Golińska, Paulina Beata Sawicki, Artur Józef Bieleninik, Łucja Bidzan, Mariola Brain Sci Article (1) Background: This study compared anterior attentional–intentional system performance between three groups: Parkinson’s disease (PD) patients with normal cognition (PD-NC), with mild cognitive impairment (PD-MCI), and a comparison group (CG). It also evaluated the feasibility of the recruitment and study procedures; (2) Methods: From 45 participants recruited, 39 were allocated (mean age 65.31; 43.59% men) to PD-NC, PD-MCI and CG (13 per group). To assess attention, we used three tasks from the ROtman–Baycrest Battery for Investigating Attention: Simple Reaction time (RT), Choice RT, and Prepare RT. We conducted a mixed-model analysis of variance with a 3 (groups) × 4 (tasks) design to compare reaction times; (3) Results: PD-MCI had slower reaction times than PD-NC (p = 0.028) and the CG (p = 0.052); there was no difference between PD-NC and CG. PD-MCI might perform worse on monitoring tasks than PD-NC, Z = −1.68, p = 0.092. Nearly half the volunteers from the CG and 87% of all eligible patients were enrolled in the study and completed all neuropsychological procedures; (4) Conclusions: General cognitive decline appears related to partial deficits in energization and tends to impair attentional monitoring. Furthermore, PD-NC exhibited similar reaction times to the CG. Results from the feasibility study contributed to the definitive study. MDPI 2021-07-30 /pmc/articles/PMC8392698/ /pubmed/34439632 http://dx.doi.org/10.3390/brainsci11081013 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Golińska, Paulina Beata Sawicki, Artur Józef Bieleninik, Łucja Bidzan, Mariola The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
title | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
title_full | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
title_fullStr | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
title_full_unstemmed | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
title_short | The Anterior Attentional–Intentional System in Patients with Parkinson’s Disease—A Pilot and Feasibility Study |
title_sort | anterior attentional–intentional system in patients with parkinson’s disease—a pilot and feasibility study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392698/ https://www.ncbi.nlm.nih.gov/pubmed/34439632 http://dx.doi.org/10.3390/brainsci11081013 |
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