Cargando…

Two-Dimensional Material-Based Colorimetric Biosensors: A Review

Two-dimensional (2D) materials such as graphene, graphene oxide, transition metal oxide, MXene and others have shown high potential for the design and fabrication of various sensors and biosensors due to their 2D layered structure and unique properties. Compared to traditional fluorescent, electroch...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Danzhu, Liu, Bin, Wei, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392748/
https://www.ncbi.nlm.nih.gov/pubmed/34436061
http://dx.doi.org/10.3390/bios11080259
_version_ 1783743575125655552
author Zhu, Danzhu
Liu, Bin
Wei, Gang
author_facet Zhu, Danzhu
Liu, Bin
Wei, Gang
author_sort Zhu, Danzhu
collection PubMed
description Two-dimensional (2D) materials such as graphene, graphene oxide, transition metal oxide, MXene and others have shown high potential for the design and fabrication of various sensors and biosensors due to their 2D layered structure and unique properties. Compared to traditional fluorescent, electrochemical, and electrical biosensors, colorimetric biosensors exhibit several advantages including naked-eye determination, low cost, quick response, and easy fabrication. In this review, we present recent advances in the design, fabrication, and applications of 2D material-based high-performance colorimetric biosensors. Potential colorimetric sensing mechanisms and optimal material selection as well as sensor fabrication are introduced in brief. In addition, colorimetric biosensors based on different 2D materials such as graphene, transition metal dichalcogenide/oxide, MXenes, metal–organic frameworks, and metal nanoplates for the sensitive detection of DNA, proteins, viruses, small molecules, metallic ions, and others are presented and discussed in detail. This work will be helpful for readers to understand the knowledge of 2D material modification, nanozymes, and the synthesis of hybrid materials; meanwhile, it could be valuable to promote the design, fabrication, and applications of 2D material-based sensors and biosensors in quick bioanalysis and disease diagnostics.
format Online
Article
Text
id pubmed-8392748
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-83927482021-08-28 Two-Dimensional Material-Based Colorimetric Biosensors: A Review Zhu, Danzhu Liu, Bin Wei, Gang Biosensors (Basel) Review Two-dimensional (2D) materials such as graphene, graphene oxide, transition metal oxide, MXene and others have shown high potential for the design and fabrication of various sensors and biosensors due to their 2D layered structure and unique properties. Compared to traditional fluorescent, electrochemical, and electrical biosensors, colorimetric biosensors exhibit several advantages including naked-eye determination, low cost, quick response, and easy fabrication. In this review, we present recent advances in the design, fabrication, and applications of 2D material-based high-performance colorimetric biosensors. Potential colorimetric sensing mechanisms and optimal material selection as well as sensor fabrication are introduced in brief. In addition, colorimetric biosensors based on different 2D materials such as graphene, transition metal dichalcogenide/oxide, MXenes, metal–organic frameworks, and metal nanoplates for the sensitive detection of DNA, proteins, viruses, small molecules, metallic ions, and others are presented and discussed in detail. This work will be helpful for readers to understand the knowledge of 2D material modification, nanozymes, and the synthesis of hybrid materials; meanwhile, it could be valuable to promote the design, fabrication, and applications of 2D material-based sensors and biosensors in quick bioanalysis and disease diagnostics. MDPI 2021-07-31 /pmc/articles/PMC8392748/ /pubmed/34436061 http://dx.doi.org/10.3390/bios11080259 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhu, Danzhu
Liu, Bin
Wei, Gang
Two-Dimensional Material-Based Colorimetric Biosensors: A Review
title Two-Dimensional Material-Based Colorimetric Biosensors: A Review
title_full Two-Dimensional Material-Based Colorimetric Biosensors: A Review
title_fullStr Two-Dimensional Material-Based Colorimetric Biosensors: A Review
title_full_unstemmed Two-Dimensional Material-Based Colorimetric Biosensors: A Review
title_short Two-Dimensional Material-Based Colorimetric Biosensors: A Review
title_sort two-dimensional material-based colorimetric biosensors: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8392748/
https://www.ncbi.nlm.nih.gov/pubmed/34436061
http://dx.doi.org/10.3390/bios11080259
work_keys_str_mv AT zhudanzhu twodimensionalmaterialbasedcolorimetricbiosensorsareview
AT liubin twodimensionalmaterialbasedcolorimetricbiosensorsareview
AT weigang twodimensionalmaterialbasedcolorimetricbiosensorsareview