Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Enterovirus 71 (EV-A71) is the main causative pathogen for severe and fatal patients with Hand, Foot, and Mouth Disease (HFMD) in mainland China from 2008 to 2017. Non-EV-A71 and non-CV-A16 (other enterovirus) serotypes were the major causative-serotypes for m...

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Autores principales: Liu, Fengfeng, Ren, Minrui, Chen, Shumin, Nie, Taoran, Cui, Jinzhao, Ran, Lu, Li, Zhongjie, Chang, Zhaorui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2020
Materias:
Preplanned Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393163/
https://www.ncbi.nlm.nih.gov/pubmed/34594617
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author Liu, Fengfeng
Ren, Minrui
Chen, Shumin
Nie, Taoran
Cui, Jinzhao
Ran, Lu
Li, Zhongjie
Chang, Zhaorui
author_facet Liu, Fengfeng
Ren, Minrui
Chen, Shumin
Nie, Taoran
Cui, Jinzhao
Ran, Lu
Li, Zhongjie
Chang, Zhaorui
author_sort Liu, Fengfeng
collection PubMed
description WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Enterovirus 71 (EV-A71) is the main causative pathogen for severe and fatal patients with Hand, Foot, and Mouth Disease (HFMD) in mainland China from 2008 to 2017. Non-EV-A71 and non-CV-A16 (other enterovirus) serotypes were the major causative-serotypes for mild HFMD in years of 2013, 2015, and 2017. WHAT IS ADDED BY THIS REPORT? In 2018, other enterovirus serotypes replaced EV-A71 for the first time as the major cause of severe HFMD with a proportion of 70.7%. However, at the national level, only a small proportion of the other enterovirus serotypes were further identified as CV-A6 and CV-A10. WHAT ARE THE LIMITATIONS FOR PUBLIC HEALTH PRACTICE? Further identification of other enterovirus serotypes is highly recommended for provincial CDCs, especially for severe HFMD. Studies contributing to a multivalent vaccine for HFMD should be prioritized.
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spelling pubmed-83931632021-09-29 Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018 Liu, Fengfeng Ren, Minrui Chen, Shumin Nie, Taoran Cui, Jinzhao Ran, Lu Li, Zhongjie Chang, Zhaorui China CDC Wkly Preplanned Studies WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? Enterovirus 71 (EV-A71) is the main causative pathogen for severe and fatal patients with Hand, Foot, and Mouth Disease (HFMD) in mainland China from 2008 to 2017. Non-EV-A71 and non-CV-A16 (other enterovirus) serotypes were the major causative-serotypes for mild HFMD in years of 2013, 2015, and 2017. WHAT IS ADDED BY THIS REPORT? In 2018, other enterovirus serotypes replaced EV-A71 for the first time as the major cause of severe HFMD with a proportion of 70.7%. However, at the national level, only a small proportion of the other enterovirus serotypes were further identified as CV-A6 and CV-A10. WHAT ARE THE LIMITATIONS FOR PUBLIC HEALTH PRACTICE? Further identification of other enterovirus serotypes is highly recommended for provincial CDCs, especially for severe HFMD. Studies contributing to a multivalent vaccine for HFMD should be prioritized. Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2020-03-14 /pmc/articles/PMC8393163/ /pubmed/34594617 Text en Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2020 https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Preplanned Studies
Liu, Fengfeng
Ren, Minrui
Chen, Shumin
Nie, Taoran
Cui, Jinzhao
Ran, Lu
Li, Zhongjie
Chang, Zhaorui
Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018
title Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018
title_full Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018
title_fullStr Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018
title_full_unstemmed Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018
title_short Pathogen Spectrum of Hand, Foot, and Mouth Disease Based on Laboratory Surveillance — China, 2018
title_sort pathogen spectrum of hand, foot, and mouth disease based on laboratory surveillance — china, 2018
topic Preplanned Studies
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393163/
https://www.ncbi.nlm.nih.gov/pubmed/34594617
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