Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? After the type 2 strain of the live, attenuated poliovirus vaccine was withdrawn globally in 2016, any identification of a type 2 poliovirus is a Public Health Emergency of International Concern. A vaccine-derived type 2 poliovirus (VDPV2) was identified in Si...

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Autores principales: Zhou, Jiushun, Wen, Ning, Zhang, Yong, Qi, Qi, Fan, Chunxiang, Yan, Dongmei, Zhu, Xiaoping, Hao, Lixin, Zhu, Shuangli, Liu, Yu, Ma, Xiaozhen, Ma, Chao, Nan, Lei, Chen, Yong, Ma, Qianli, Wang, Cheng, Deng, Kun, Cao, Lei, Shao, Ge, Ding, Xianxiang, Yang, Hong, An, Zhijie, Rodewald, Lance E., Xu, Aiqiang, Wang, Huaqing, Feng, Zijian, Yin, Zundong, Wu, Xianping, Xu, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2020
Materias:
Outbreak Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393164/
https://www.ncbi.nlm.nih.gov/pubmed/34594618
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author Zhou, Jiushun
Wen, Ning
Zhang, Yong
Qi, Qi
Fan, Chunxiang
Yan, Dongmei
Zhu, Xiaoping
Hao, Lixin
Zhu, Shuangli
Liu, Yu
Ma, Xiaozhen
Ma, Chao
Nan, Lei
Chen, Yong
Ma, Qianli
Wang, Cheng
Deng, Kun
Cao, Lei
Shao, Ge
Ding, Xianxiang
Yang, Hong
An, Zhijie
Rodewald, Lance E.
Xu, Aiqiang
Wang, Huaqing
Feng, Zijian
Yin, Zundong
Wu, Xianping
Xu, Wenbo
author_facet Zhou, Jiushun
Wen, Ning
Zhang, Yong
Qi, Qi
Fan, Chunxiang
Yan, Dongmei
Zhu, Xiaoping
Hao, Lixin
Zhu, Shuangli
Liu, Yu
Ma, Xiaozhen
Ma, Chao
Nan, Lei
Chen, Yong
Ma, Qianli
Wang, Cheng
Deng, Kun
Cao, Lei
Shao, Ge
Ding, Xianxiang
Yang, Hong
An, Zhijie
Rodewald, Lance E.
Xu, Aiqiang
Wang, Huaqing
Feng, Zijian
Yin, Zundong
Wu, Xianping
Xu, Wenbo
author_sort Zhou, Jiushun
collection PubMed
description WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? After the type 2 strain of the live, attenuated poliovirus vaccine was withdrawn globally in 2016, any identification of a type 2 poliovirus is a Public Health Emergency of International Concern. A vaccine-derived type 2 poliovirus (VDPV2) was identified in Sichuan, prompting an urgent, comprehensive investigation and response. WHAT IS ADDED BY THIS REPORT? Type 2 monovalent, live, attenuated oral poliovirus vaccine (mOPV2) is being used to respond to the numerous VDPV2 outbreaks seen around the world. In contrast, the response in Sichuan used Sabin strain inactivated poliovirus (sIPV) to stop circulation of the VDPV2. In the 6 months following the vaccination response, there have been no VDPV2s detected in Sichuan, despite extensive search. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICES? Further search for the VDPV2 must continue in order to determine whether transmission has been stopped. The ongoing investigation and response to the Sichuan VDPV2 is providing evidence to the Global Polio Eradication Initiative on managing VDPV2 outbreaks.
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spelling pubmed-83931642021-09-29 Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019 Zhou, Jiushun Wen, Ning Zhang, Yong Qi, Qi Fan, Chunxiang Yan, Dongmei Zhu, Xiaoping Hao, Lixin Zhu, Shuangli Liu, Yu Ma, Xiaozhen Ma, Chao Nan, Lei Chen, Yong Ma, Qianli Wang, Cheng Deng, Kun Cao, Lei Shao, Ge Ding, Xianxiang Yang, Hong An, Zhijie Rodewald, Lance E. Xu, Aiqiang Wang, Huaqing Feng, Zijian Yin, Zundong Wu, Xianping Xu, Wenbo China CDC Wkly Outbreak Reports WHAT IS ALREADY KNOWN ABOUT THIS TOPIC? After the type 2 strain of the live, attenuated poliovirus vaccine was withdrawn globally in 2016, any identification of a type 2 poliovirus is a Public Health Emergency of International Concern. A vaccine-derived type 2 poliovirus (VDPV2) was identified in Sichuan, prompting an urgent, comprehensive investigation and response. WHAT IS ADDED BY THIS REPORT? Type 2 monovalent, live, attenuated oral poliovirus vaccine (mOPV2) is being used to respond to the numerous VDPV2 outbreaks seen around the world. In contrast, the response in Sichuan used Sabin strain inactivated poliovirus (sIPV) to stop circulation of the VDPV2. In the 6 months following the vaccination response, there have been no VDPV2s detected in Sichuan, despite extensive search. WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICES? Further search for the VDPV2 must continue in order to determine whether transmission has been stopped. The ongoing investigation and response to the Sichuan VDPV2 is providing evidence to the Global Polio Eradication Initiative on managing VDPV2 outbreaks. Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2020-03-14 /pmc/articles/PMC8393164/ /pubmed/34594618 Text en Copyright and License information: Editorial Office of CCDCW, Chinese Center for Disease Control and Prevention 2020 https://creativecommons.org/licenses/by-nc-sa/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Outbreak Reports
Zhou, Jiushun
Wen, Ning
Zhang, Yong
Qi, Qi
Fan, Chunxiang
Yan, Dongmei
Zhu, Xiaoping
Hao, Lixin
Zhu, Shuangli
Liu, Yu
Ma, Xiaozhen
Ma, Chao
Nan, Lei
Chen, Yong
Ma, Qianli
Wang, Cheng
Deng, Kun
Cao, Lei
Shao, Ge
Ding, Xianxiang
Yang, Hong
An, Zhijie
Rodewald, Lance E.
Xu, Aiqiang
Wang, Huaqing
Feng, Zijian
Yin, Zundong
Wu, Xianping
Xu, Wenbo
Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019
title Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019
title_full Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019
title_fullStr Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019
title_full_unstemmed Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019
title_short Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus — Sichuan Province, China, 2019
title_sort detection and initial response to a type 2 vaccine-derived poliovirus — sichuan province, china, 2019
topic Outbreak Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393164/
https://www.ncbi.nlm.nih.gov/pubmed/34594618
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