Cargando…

Pinocembrin Ameliorates Skin Fibrosis via Inhibiting TGF-β1 Signaling Pathway

Skin fibrotic diseases, such as keloids, are mainly caused by pathologic scarring of wounds during healing and characterized by benign cutaneous overgrowths of dermal fibroblasts. Current surgical and therapeutic modalities of skin fibrosis are unsatisfactory. Pinocembrin, a natural flavonoid, has b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Xiaohe, Zhai, Yunqian, Xi, Buri, Ma, Wei, Zhang, Jianwei, Ma, Xiaoyang, Miao, Yang, Zhao, Yongjian, Ning, Wen, Zhou, Honggang, Yang, Cheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393190/ https://www.ncbi.nlm.nih.gov/pubmed/34439906 http://dx.doi.org/10.3390/biom11081240

Ejemplares similares

Duvelisib attenuates bleomycin‐induced pulmonary fibrosis via inhibiting the PI3K/Akt/mTOR signalling pathway
por: Li, Xiaohe, et al.
Publicado: (2023)

Pinocembrin ameliorates arrhythmias in rats with chronic ischaemic heart failure
por: Guo, Yan, et al.
Publicado: (2021)

Regorafenib-Attenuated, Bleomycin-Induced Pulmonary Fibrosis by Inhibiting the TGF-β1 Signaling Pathway
por: Li, Xiaohe, et al.
Publicado: (2021)

PKM2 promotes pulmonary fibrosis by stabilizing TGF-β1 receptor I and enhancing TGF-β1 signaling
por: Gao, Shaoyan, et al.
Publicado: (2022)

Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation
por: Liu, Peng, et al.
Publicado: (2020)

Correction to: Curdione ameliorates bleomycin-induced pulmonary fibrosis by repressing TGF-β-induced fibroblast to myofibroblast differentiation
por: Liu, Peng, et al.
Publicado: (2023)

Deglycosylated Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis via the TGF-β1 Signaling Pathway
por: Ruan, Hao, et al.
Publicado: (2021)

Baricitinib Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice by Inhibiting TGF-β1 Signaling Pathway
por: Gu, Songtao, et al.
Publicado: (2023)

Pinocembrin ameliorates atrial fibrillation susceptibility in rats with anxiety disorder induced by empty bottle stimulation
por: Ran, Qian, et al.
Publicado: (2022)

Pinocembrin Ameliorates Cognitive Impairment Induced by Vascular Dementia: Contribution of Reelin-dab1 Signaling Pathway
por: Kang, Ze-Chun, et al.
Publicado: (2020)

The efficacy and safety of pinocembrin in a sheep model of bleomycin-induced pulmonary fibrosis
por: Derseh, Habtamu B., et al.
Publicado: (2021)

Blockade of TGF-β/Smad signaling by the small compound HPH-15 ameliorates experimental skin fibrosis
por: Luong, Vu Huy, et al.
Publicado: (2018)

Optimization of Pinocembrin Biosynthesis in Saccharomyces cerevisiae
por: Tous Mohedano, Marta, et al.
Publicado: (2022)

Pinocembrin ameliorates post-infarct heart failure through activation of Nrf2/HO-1 signaling pathway
por: Chen, Xiuhuan, et al.
Publicado: (2021)

Pinocembrin–Lecithin Complex: Characterization, Solubilization, and Antioxidant Activities
por: Yang, Xu, et al.
Publicado: (2018)

Andrographolide Ameliorates Liver Fibrosis in Mice: Involvement of TLR4/NF-κB and TGF-β1/Smad2 Signaling Pathways
por: Lin, Liteng, et al.
Publicado: (2018)

Canagliflozin and irbesartan ameliorate renal fibrosis via the TGF-β1/Smad signaling pathway in Dahl salt-sensitive rats
por: Zhai, Jianlong, et al.
Publicado: (2023)

Fedratinib Attenuates Bleomycin-Induced Pulmonary Fibrosis via the JAK2/STAT3 and TGF-β1 Signaling Pathway
por: Ruan, Hao, et al.
Publicado: (2021)

The Anti-Campylobacter Activity and Mechanisms of Pinocembrin Action
por: Klančnik, Anja, et al.
Publicado: (2019)

Pinocembrin ameliorates lipopolysaccharide-induced HK-2 cell apoptosis and inflammation by regulating endoplasmic reticulum stress
por: Zhang, Yu, et al.
Publicado: (2022)

Sorafenib Ameliorates Renal Fibrosis through Inhibition of TGF-β-Induced Epithelial-Mesenchymal Transition
por: Jia, Lining, et al.
Publicado: (2015)

Dalbergioidin Ameliorates Doxorubicin-Induced Renal Fibrosis by Suppressing the TGF-β Signal Pathway
por: Ren, Xianguo, et al.
Publicado: (2016)

The inhibition of calpains ameliorates vascular restenosis through MMP2/TGF-β1 pathway
por: Tang, Lianghu, et al.
Publicado: (2016)

Enhanced pinocembrin production in Escherichia coli by regulating cinnamic acid metabolism
por: Cao, Weijia, et al.
Publicado: (2016)

Shenqiwan Ameliorates Renal Fibrosis in Rats by Inhibiting TGF-β1/Smads Signaling Pathway
por: Chen, Hongshu, et al.
Publicado: (2017)

Pinocembrin mitigates depressive-like behaviors induced by chronic unpredictable mild stress through ameliorating neuroinflammation and apoptosis
por: Wang, Wei, et al.
Publicado: (2020)

Imrecoxib attenuates bleomycin-induced pulmonary fibrosis in mice
por: Miao, Yang, et al.
Publicado: (2023)

In-vivo absorption of pinocembrin-7-O-β-D-glucoside in rats and its in-vitro biotransformation
por: Guo, Wei-Wei, et al.
Publicado: (2016)

Pinocembrin Decreases Atrial Fibrillation Susceptibility in a Rodent Model of Depression
por: Ran, Qian, et al.
Publicado: (2022)

Pinocembrin Decreases Ventricular Fibrillation Susceptibility in a Rat Model of Depression
por: Ye, Tianxin, et al.
Publicado: (2020)

Regulation of ATP levels in Escherichia coli using CRISPR interference for enhanced pinocembrin production
por: Tao, Sha, et al.
Publicado: (2018)

Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Pathway in Diabetic Mice
por: Huang, Chunling, et al.
Publicado: (2013)

Zanubrutinib Ameliorates Cardiac Fibrosis and Inflammation Induced by Chronic Sympathetic Activation
por: Li, Wenqi, et al.
Publicado: (2023)

Byakangelicin protects against carbon tetrachloride–induced liver injury and fibrosis in mice
por: Li, Xiaohe, et al.
Publicado: (2020)

H(2)S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression
por: Li, Yan, et al.
Publicado: (2016)

Dendropanax morbifera Ameliorates Thioacetamide-Induced Hepatic Fibrosis via TGF-β1/Smads Pathways
por: Yang, Hun Yong, et al.
Publicado: (2019)

Astragaloside IV Synergizing with Ferulic Acid Ameliorates Pulmonary Fibrosis by TGF-β1/Smad3 Signaling
por: Tong, Jiahuan, et al.
Publicado: (2021)

Pinocembrin ameliorates intermittent hypoxia-induced neuroinflammation through BNIP3-dependent mitophagy in a murine model of sleep apnea
por: Gong, Lin-Jing, et al.
Publicado: (2020)

Tubastatin ameliorates pulmonary fibrosis by targeting the TGFβ-PI3K-Akt pathway
por: Saito, Shigeki, et al.
Publicado: (2017)

Corrigendum: Pinocembrin Decreases Ventricular Fibrillation Susceptibility in a Rat Model of Depression
por: Ye, Tianxin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ubvfcpcjk7p6tgcu0a90651o4o