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Total Syntheses of the C(19) Diterpenoid Alkaloids (−)-Talatisamine, (−)-Liljestrandisine, and (−)-Liljestrandinine by a Fragment Coupling Approach

[Image: see text] The C19 diterpenoid alkaloids (C19 DTAs) are a large family of natural products, many of which modulate the activity of ion channels in vivo and are therefore of interest for the study of neurological and cardiovascular diseases. The complex architectures of these molecules continu...

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Detalles Bibliográficos
Autores principales: Wong, Alice R., Fastuca, Nicholas J., Mak, Victor W., Kerkovius, Jeffrey K., Stevenson, Susan M., Reisman, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393236/
https://www.ncbi.nlm.nih.gov/pubmed/34471676
http://dx.doi.org/10.1021/acscentsci.1c00540