Imaging-Guided Therapy Simultaneously Targeting HER2 and EpCAM with Trastuzumab and EpCAM-Directed Toxin Provides Additive Effect in Ovarian Cancer Model

SIMPLE SUMMARY: Targeted therapeutics provide cytostatic or cytotoxic action selectively to tumor cells while reducing the toxicity to normal cells. Targeting two molecular receptors overexpressed on tumor cells is a way to overcome heterogeneity of expression and improve therapeutic efficacy. Combi...

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Detalles Bibliográficos
Autores principales: Xu, Tianqi, Vorobyeva, Anzhelika, Schulga, Alexey, Konovalova, Elena, Vorontsova, Olga, Ding, Haozhong, Gräslund, Torbjörn, Tashireva, Liubov A., Orlova, Anna, Tolmachev, Vladimir, Deyev, Sergey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393281/
https://www.ncbi.nlm.nih.gov/pubmed/34439094
http://dx.doi.org/10.3390/cancers13163939

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