Cargando…

Soluble Guanylate Cyclase Stimulator Vericiguat Enhances Long-Term Memory in Rats without Altering Cerebral Blood Volume

Vascular cognitive impairment (VCI) is characterized by impairments in cerebral blood flow (CBF), endothelial function and blood–brain barrier (BBB) integrity. These processes are all physiologically regulated by the nitric oxide (NO)-soluble guanylate cyclase (sGC)-cGMP signaling pathway. Additiona...

Descripción completa

Detalles Bibliográficos
Autores principales: Nelissen, Ellis, Argyrousi, Elentina K., Van Goethem, Nick P., Zhao, Fuqiang, Hines, Catherine D. G., Swaminath, Gayathri, Gerisch, Michael, Hueser, Joerg, Sandner, Peter, Prickaerts, Jos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393324/
https://www.ncbi.nlm.nih.gov/pubmed/34440254
http://dx.doi.org/10.3390/biomedicines9081047