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A Thermodynamic Analysis of the Binding Specificity between Four Human PDZ Domains and Eight Host, Viral and Designed Ligands

PDZ domains are binding modules mostly involved in cell signaling and cell–cell junctions. These domains are able to recognize a wide variety of natural targets and, among the PDZ partners, viruses have been discovered to interact with their host via a PDZ domain. With such an array of relevant and...

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Detalles Bibliográficos
Autores principales:	Cobos, Eva S., Sánchez, Ignacio E., Chemes, Lucía B., Martinez, Jose C., Murciano-Calles, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393326/ https://www.ncbi.nlm.nih.gov/pubmed/34439737 http://dx.doi.org/10.3390/biom11081071

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