In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution

Humanized mouse models generated with human hematopoietic stem cells (HSCs) and reconstituting the human immune system (HIS-mice) are invigorating preclinical testing of vaccines and immunotherapies. We have recently shown that human engineered dendritic cells boosted bonafide human T and B cell mat...

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Detalles Bibliográficos
Autores principales: Kumar, Suresh, Koenig, Johannes, Schneider, Andreas, Wermeling, Fredrik, Boddul, Sanjaykumar, Theobald, Sebastian J., Vollmer, Miriam, Kloos, Doreen, Lachmann, Nico, Klawonn, Frank, Lienenklaus, Stefan, Talbot, Steven R., Bleich, André, Wenzel, Nadine, von Kaisenberg, Constantin, Keck, James, Stripecke, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393476/
https://www.ncbi.nlm.nih.gov/pubmed/34440166
http://dx.doi.org/10.3390/biomedicines9080961

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393476/
https://www.ncbi.nlm.nih.gov/pubmed/34440166
http://dx.doi.org/10.3390/biomedicines9080961

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