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In Vivo Lentiviral Gene Delivery of HLA-DR and Vaccination of Humanized Mice for Improving the Human T and B Cell Immune Reconstitution

Humanized mouse models generated with human hematopoietic stem cells (HSCs) and reconstituting the human immune system (HIS-mice) are invigorating preclinical testing of vaccines and immunotherapies. We have recently shown that human engineered dendritic cells boosted bonafide human T and B cell mat...

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Detalles Bibliográficos
Autores principales:	Kumar, Suresh, Koenig, Johannes, Schneider, Andreas, Wermeling, Fredrik, Boddul, Sanjaykumar, Theobald, Sebastian J., Vollmer, Miriam, Kloos, Doreen, Lachmann, Nico, Klawonn, Frank, Lienenklaus, Stefan, Talbot, Steven R., Bleich, André, Wenzel, Nadine, von Kaisenberg, Constantin, Keck, James, Stripecke, Renata
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393476/ https://www.ncbi.nlm.nih.gov/pubmed/34440166 http://dx.doi.org/10.3390/biomedicines9080961

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