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MiRNAs Correlate with HLA Expression in Uveal Melanoma: Both Up- and Downregulation Are Related to Monosomy 3

SIMPLE SUMMARY: Uveal melanoma (UM) is a rare ocular malignancy that often gives rise to metastases. Tumours with an inflammatory phenotype have an especially bad prognosis. As an increased HLA expression and the presence of tumour-infiltrating lymphocytes and macrophages may be regulated by miRNAs,...

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Detalles Bibliográficos
Autores principales: Souri, Zahra, Wierenga, Annemijn P. A., Kiliç, Emine, Brosens, Erwin, Böhringer, Stefan, Kroes, Wilma G. M., Verdijk, Robert M., van der Velden, Pieter A., Luyten, Gregorius P. M., Jager, Martine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393554/
https://www.ncbi.nlm.nih.gov/pubmed/34439175
http://dx.doi.org/10.3390/cancers13164020