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Comparison of Quantification of Target-Specific Accumulation of [(18)F]F-siPSMA-14 in the HET-CAM Model and in Mice Using PET/MRI
SIMPLE SUMMARY: Animal studies are essential for the development of new radiopharmaceuticals to determine specific accumulation and biodistribution. Alternative models, such as the HET-CAM model, offer the possibility of reducing animal experiments in accordance with the 3Rs principles. Accurate qua...
Autores principales: | Löffler, Jessica, Hamp, Carmen, Scheidhauer, Ellen, Di Carlo, Daniel, Solbach, Christoph, Abaei, Alireza, Hao, Li, Glatting, Gerhard, Beer, Ambros J., Rasche, Volker, Winter, Gordon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393674/ https://www.ncbi.nlm.nih.gov/pubmed/34439163 http://dx.doi.org/10.3390/cancers13164007 |
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