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MEN1 silencing aggravates tumorigenic potential of AR-independent prostate cancer cells through nuclear translocation and activation of JunD and β-catenin

BACKGROUND: Recent studies highlighted the increased frequency of AR-low or -negative prostate cancers (PCas) and the importance of AR-independent mechanisms in driving metastatic castration-resistant PCa (mCRPC) development and progression. Several previous studies have highlighted the involvement...

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Detalles Bibliográficos
Autores principales: Luo, Yakun, Vlaeminck-Guillem, Virginie, Baron, Silvère, Dallel, Sarah, Zhang, Chang Xian, Le Romancer, Muriel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393735/
https://www.ncbi.nlm.nih.gov/pubmed/34446068
http://dx.doi.org/10.1186/s13046-021-02058-7