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Betamethasone administration during pregnancy is associated with placental epigenetic changes with implications for inflammation

BACKGROUND: Glucocorticoids (GCs) play a pivotal role in fetal programming. Antenatal treatment with synthetic GCs (sGCs) in individuals in danger of preterm labor is common practice. Adverse short- and long-term effects of antenatal sGCs have been reported, but their effects on placental epigenetic...

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Detalles Bibliográficos
Autores principales: Czamara, Darina, Dieckmann, Linda, Röh, Simone, Kraemer, Sarah, Rancourt, Rebecca C., Sammallahti, Sara, Kajantie, Eero, Laivuori, Hannele, Eriksson, Johan G., Räikkönen, Katri, Henrich, Wolfgang, Plagemann, Andreas, Binder, Elisabeth B., Braun, Thorsten, Entringer, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393766/
https://www.ncbi.nlm.nih.gov/pubmed/34446099
http://dx.doi.org/10.1186/s13148-021-01153-y