Bridging Offline Functional Model Carrying Aging-Specific Growth Rate Information and Recombinant Protein Expression: Entropic Extension of Akaike Information Criterion

This study presents a mathematical model of recombinant protein expression, including its development, selection, and fitting results based on seventy fed-batch cultivation experiments from two independent biopharmaceutical sites. To resolve the overfitting feature of the Akaike information criterio...

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Detalles Bibliográficos
Autores principales: Urniezius, Renaldas, Kemesis, Benas, Simutis, Rimvydas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393800/
https://www.ncbi.nlm.nih.gov/pubmed/34441197
http://dx.doi.org/10.3390/e23081057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393800/
https://www.ncbi.nlm.nih.gov/pubmed/34441197
http://dx.doi.org/10.3390/e23081057

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