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The mechanism of Annexin A1 to modulate TRPV1 and nociception in dorsal root ganglion neurons

BACKGROUND: Annexin A1 (ANXA1) exerts anti-nociceptive effect through ANXA1 receptor formyl peptide receptor 2 (FPR2/ALX (receptor for lipoxin A4), FPR2) at the dorsal root ganglia (DRG) level. However, the mechanisms remain elucidated. By using radiant heat, hot/cold plate, tail flick, von Frey, an...

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Detalles Bibliográficos
Autores principales: Zhang, Yufen, Ma, Sehui, Ke, Xiao, Yi, Yao, Yu, Hongyan, Yu, Dian, Li, Qiang, Shang, You, Lu, Youming, Pei, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393810/
https://www.ncbi.nlm.nih.gov/pubmed/34446102
http://dx.doi.org/10.1186/s13578-021-00679-1