Cargando…

Targeted Lipidomics of Mitochondria in a Cellular Alzheimer’s Disease Model

Alzheimer’s disease (AD) is neuropathologically characterized by the accumulation of Amyloid-β (Aβ) in senile plaques derived from amyloidogenic processing of a precursor protein (APP). Recently, changes in mitochondrial function have become in the focus of the disease. Whereas a link between AD and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kurokin, Irina, Lauer, Anna Andrea, Janitschke, Daniel, Winkler, Jakob, Theiss, Elena Leoni, Griebsch, Lea Victoria, Pilz, Sabrina Melanie, Matschke, Veronika, van der Laan, Martin, Grimm, Heike Sabine, Hartmann, Tobias, Grimm, Marcus Otto Walter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393816/ https://www.ncbi.nlm.nih.gov/pubmed/34440266 http://dx.doi.org/10.3390/biomedicines9081062

Ejemplares similares

Methylxanthines Induce a Change in the AD/Neurodegeneration-Linked Lipid Profile in Neuroblastoma Cells
por: Janitschke, Daniel, et al.
Publicado: (2022)

Impact of Vitamin D(3) Deficiency on Phosphatidylcholine-/Ethanolamine, Plasmalogen-, Lyso-Phosphatidylcholine-/Ethanolamine, Carnitine- and Triacyl Glyceride-Homeostasis in Neuroblastoma Cells and Murine Brain
por: Lauer, Anna Andrea, et al.
Publicado: (2021)

Aspartame and Its Metabolites Cause Oxidative Stress and Mitochondrial and Lipid Alterations in SH-SY5Y Cells
por: Griebsch, Lea Victoria, et al.
Publicado: (2023)

Medium-Chain Length Fatty Acids Enhance Aβ Degradation by Affecting Insulin-Degrading Enzyme
por: Mett, Janine, et al.
Publicado: (2021)

Vitamin B12 Attenuates Changes in Phospholipid Levels Related to Oxidative Stress in SH-SY5Y Cells
por: Theiss, Elena Leoni, et al.
Publicado: (2022)

Effect of Caffeine and Other Methylxanthines on Aβ-Homeostasis in SH-SY5Y Cells
por: Janitschke, Daniel, et al.
Publicado: (2019)

The Influence of Acitretin on Brain Lipidomics in Adolescent Mice—Implications for Pediatric and Adolescent Dermatological Therapy
por: Lauer, Anna A., et al.
Publicado: (2022)

Gemfibrozil-Induced Intracellular Triglyceride Increase in SH-SY5Y, HEK and Calu-3 Cells
por: Bachmann, Cornel Manuel, et al.
Publicado: (2023)

Shotgun lipidomics of liver and brain tissue of Alzheimer’s disease model mice treated with acitretin
por: Lauer, Anna A., et al.
Publicado: (2021)

Methylxanthines and Neurodegenerative Diseases: An Update
por: Janitschke, Daniel, et al.
Publicado: (2021)

Unique Role of Caffeine Compared to Other Methylxanthines (Theobromine, Theophylline, Pentoxifylline, Propentofylline) in Regulation of AD Relevant Genes in Neuroblastoma SH-SY5Y Wild Type Cells
por: Janitschke, Daniel, et al.
Publicado: (2020)

Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation
por: Grimm, Marcus O. W., et al.
Publicado: (2017)

Vitamin D and Its Analogues: From Differences in Molecular Mechanisms to Potential Benefits of Adapted Use in the Treatment of Alzheimer’s Disease
por: Thiel, Andrea, et al.
Publicado: (2023)

The impact of capsaicinoids on APP processing in Alzheimer’s disease in SH-SY5Y cells
por: Grimm, Marcus O. W., et al.
Publicado: (2020)

Oxidative stress: the lowest common denominator of multiple diseases
por: Matschke, Veronika, et al.
Publicado: (2019)

Interprofessional education: a necessity in Alzheimer’s dementia care—a pilot study
por: Dressel, Katharina, et al.
Publicado: (2023)

Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis
por: Stein, Jan, et al.
Publicado: (2021)

Regulatory feedback cycle of the insulin‐degrading enzyme and the amyloid precursor protein intracellular domain: Implications for Alzheimer’s disease
por: Lauer, Anna A., et al.
Publicado: (2020)

Caffeine and NAD(+) Improve Motor Neural Integrity of Dissociated Wobbler Cells In Vitro
por: Zwilling, Mareike, et al.
Publicado: (2020)

Significance of intercellular communication for neurodegenerative diseases
por: Cihankaya, Hilal, et al.
Publicado: (2021)

Little Helpers or Mean Rogue—Role of Microglia in Animal Models of Amyotrophic Lateral Sclerosis
por: Cihankaya, Hilal, et al.
Publicado: (2021)

Teriflunomide provides protective properties after oxygen-glucose-deprivation in hippocampal and cerebellar slice cultures
por: Wolters, Anna, et al.
Publicado: (2021)

Interdisciplinary Approaches to Deal with Alzheimer’s Disease—From Bench to Bedside: What Feasible Options Do Already Exist Today?
por: Ablinger, Irene, et al.
Publicado: (2022)

PEX19 Coordinates Neutral Lipid Storage in Cells in a Peroxisome-Independent Fashion
por: Lyschik, Sven, et al.
Publicado: (2022)

Defects in Glutathione System in an Animal Model of Amyotrophic Lateral Sclerosis
por: Wunsch, Franziska T., et al.
Publicado: (2023)

Mechanistic Link between Vitamin B12 and Alzheimer’s Disease
por: Lauer, Anna Andrea, et al.
Publicado: (2022)

Mitochondria, Estrogen and Female Brain Aging
por: Lejri, Imane, et al.
Publicado: (2018)

Deregulated miR-29b-3p Correlates with Tissue-Specific Activation of Intrinsic Apoptosis in An Animal Model of Amyotrophic Lateral Sclerosis
por: Klatt, Christina L., et al.
Publicado: (2019)

Cigarette smoke causes a bioenergetic crisis in RPE cells involving the downregulation of HIF-1α under normoxia
por: Henning, Yoshiyuki, et al.
Publicado: (2023)

Mitochondria Transfer in Brain Injury and Disease
por: Fairley, Lauren H., et al.
Publicado: (2022)

Insights into Disease-Associated Tau Impact on Mitochondria
por: Szabo, Leonora, et al.
Publicado: (2020)

APP Function and Lipids: A Bidirectional Link
por: Grimm, Marcus O. W., et al.
Publicado: (2017)

Morphological Plasticity of Emerging Purkinje Cells in Response to Exogenous VEGF
por: Herrfurth, Leonard, et al.
Publicado: (2017)

miR-129-5p and miR-130a-3p Regulate VEGFR-2 Expression in Sensory and Motor Neurons during Development
por: Glaesel, Kevin, et al.
Publicado: (2020)

Lipidomic Alterations in the Mitochondria of Aged Parkin Null Mice Relevant to Autophagy
por: Gaudioso, Angel, et al.
Publicado: (2019)

ROS scavengers decrease γH2ax spots in motor neuronal nuclei of ALS model mice in vitro
por: Junghans, Maya, et al.
Publicado: (2022)

Vascular Endothelial Growth Factor, Irradiation, and Axitinib Have Diverse Effects on Motility and Proliferation of Glioblastoma Multiforme Cells
por: Krcek, Reinhardt, et al.
Publicado: (2017)

Identifying mitotane-induced mitochondria-associated membranes dysfunctions: metabolomic and lipidomic approaches
por: Hescot, Ségolène, et al.
Publicado: (2017)

Defining the lipidome of Arabidopsis leaf mitochondria: Specific lipid complement and biosynthesis capacity
por: Liu, Yi-Tse, et al.
Publicado: (2023)

Effects of progesterone on T-type-Ca(2+)-channel expression in Purkinje cells
por: Eickhoff, Annika, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_p179qtrscq4nld8sjmd9kh2t43