Cargando…

Network-Based Integration of Multi-Omics Data Identifies the Determinants of miR-491-5p Effects

SIMPLE SUMMARY: The re-introduction of miRNAs with tumor-suppressor activity in cancer cells has not yet been implemented in clinical practice yet. However, the identification of miRNAs’ targets and associated regulatory networks might allow the definition of new strategies using drugs whose associa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meryet-Figuiere, Matthieu, Vernon, Mégane, Andrianteranagna, Mamy, Lambert, Bernard, Brochen, Célia, Issartel, Jean-Paul, Guttin, Audrey, Gauduchon, Pascal, Brotin, Emilie, Dingli, Florent, Loew, Damarys, Vigneron, Nicolas, Wambecke, Anaïs, Abeilard, Edwige, Barillot, Emmanuel, Poulain, Laurent, Martignetti, Loredana, Denoyelle, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393872/ https://www.ncbi.nlm.nih.gov/pubmed/34439123 http://dx.doi.org/10.3390/cancers13163970

Ejemplares similares

The lncRNA ‘UCA1’ modulates the response to chemotherapy of ovarian cancer through direct binding to miR‐27a‐5p and control of UBE2N levels
por: Wambecke, Anaïs, et al.
Publicado: (2021)

miR-491-5p-induced apoptosis in ovarian carcinoma depends on the direct inhibition of both BCL-X(L) and EGFR leading to BIM activation
por: Denoyelle, C, et al.
Publicado: (2014)

An overview of long non-coding RNAs in ovarian cancers
por: Meryet-Figuière, Matthieu, et al.
Publicado: (2016)

Towards a new standardized method for circulating miRNAs profiling in clinical studies: Interest of the exogenous normalization to improve miRNA signature accuracy
por: Vigneron, Nicolas, et al.
Publicado: (2016)

Involvement of lncRNAs in cancer cells migration, invasion and metastasis: cytoskeleton and ECM crosstalk
por: Ahmad, Mohammad, et al.
Publicado: (2023)

Sensitization of ovarian carcinoma cells to Bcl-x(L)-targeting strategies through indirect modulation of Mcl-1 activity by MR22388, a molecule of the tripentone family
por: Tomasina, Julie, et al.
Publicado: (2013)

Atelocollagen-mediated in vivo siRNA transfection in ovarian carcinoma is influenced by tumor site, siRNA target and administration route
por: Meryet-Figuière, Matthieu, et al.
Publicado: (2017)

Calcium signals inhibition sensitizes ovarian carcinoma cells to anti-Bcl-x(L) strategies through Mcl-1 down-regulation
por: Bonnefond, Marie-Laure, et al.
Publicado: (2015)

Comparative analysis of response to treatments and molecular features of tumor-derived organoids versus cell lines and PDX derived from the same ovarian clear cell carcinoma
por: Thorel, Lucie, et al.
Publicado: (2023)

Tumor Suppressive Role of miR-342-5p and miR-491-5p in Human Osteosarcoma Cells
por: Veys, Clément, et al.
Publicado: (2022)

Bim, Puma and Noxa upregulation by Naftopidil sensitizes ovarian cancer to the BH3-mimetic ABT-737 and the MEK inhibitor Trametinib
por: Florent, Romane, et al.
Publicado: (2020)

Synergy of the microRNA Ratio as a Promising Diagnosis Biomarker for Mucinous Borderline and Malignant Ovarian Tumors
por: Dolivet, Enora, et al.
Publicado: (2023)

Inhibition of store-operated channels by carboxyamidotriazole sensitizes ovarian carcinoma cells to anti-Bclx(L) strategies through Mcl-1 down-regulation
por: Bonnefond, Marie-Laure, et al.
Publicado: (2018)

Computational identification of transcriptionally co-regulated genes, validation with the four ANT isoform genes
por: Dupont, Pierre-Yves, et al.
Publicado: (2012)

Evaluation of the potential of a new ribavirin analog impairing the dissemination of ovarian cancer cells
por: Wambecke, Anaïs, et al.
Publicado: (2019)

Histone variant H3.3 residue S31 is essential for Xenopus gastrulation regardless of the deposition pathway
por: Sitbon, David, et al.
Publicado: (2020)

Dysregulated expression of long noncoding RNAs in gynecologic cancers
por: Hosseini, Elahe Seyed, et al.
Publicado: (2017)

MiR-4270 acts as a tumor suppressor by directly targeting Bcl-xL in human osteosarcoma cells
por: Veys, Clément, et al.
Publicado: (2023)

Inhibition of Mcl-1 expression by citrate enhances the effect of Bcl-x(L) inhibitors on human ovarian carcinoma cells
por: Lincet, Hubert, et al.
Publicado: (2013)

SUN-491 An Uncommon Presentation of Primary Hiperparathyroidism
por: Bastos, Filipa, et al.
Publicado: (2019)

Alternative splicing of clathrin heavy chain contributes to the switch from coated pits to plaques
por: Moulay, Gilles, et al.
Publicado: (2020)

Tumor Suppressive Role of miR-342-5p in Human Chondrosarcoma Cells and 3D Organoids
por: Veys, Clément, et al.
Publicado: (2021)

Discovery of RUF6 ncRNA–interacting proteins involved in P. falciparum immune evasion
por: Diffendall, Gretchen M, et al.
Publicado: (2022)

ODP491 Levothyroxine Withdrawal Presenting as Myxedema Madness
por: Trusty, Rhonda-Kaye, et al.
Publicado: (2022)

491 Outcomes of an Integrated Research Ethics Consultation Service
por: Smith, Elise, et al.
Publicado: (2023)

Immunoprecipitation and mass spectrometry identify non-cell autonomous Otx2 homeoprotein in the granular and supragranular layers of mouse visual cortex
por: Kim, Namsuk, et al.
Publicado: (2014)

Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons
por: Fossati, Matteo, et al.
Publicado: (2019)

Phenotypic and proteomic analysis of plasma extracellular vesicles highlights them as potential biomarkers of primary Sjögren syndrome
por: Ferrant, Juliette, et al.
Publicado: (2023)

491 Immunotherapy (IT) Training in Canada: Current Experience of Fellows-in-training
por: Pun, Teresa, et al.
Publicado: (2012)

SAT-491 Severe Hypercalcemia Secondary to Primary Skeletal Sarcoidosis
por: Dbeis, Ammer, et al.
Publicado: (2019)

FRI491 The Impact Of Insulin Resistance On Thyroid Function In Pregnancy
por: Trofimiuk-Muldner, Malgorzata, et al.
Publicado: (2023)

THU491 GRHL2 Overexpression In Breast Cancer Progression
por: Zheng, Christy, et al.
Publicado: (2023)

PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
por: Ali, Mohamad Moustafa, et al.
Publicado: (2018)

DNA-PK Target Identification Reveals Novel Links between DNA Repair Signaling and Cytoskeletal Regulation
por: Kotula, Ewa, et al.
Publicado: (2013)

Identification of the Host Substratome of Leishmania-Secreted Casein Kinase 1 Using a SILAC-Based Quantitative Mass Spectrometry Assay
por: Smirlis, Despina, et al.
Publicado: (2022)

ATRT-27. COST-EFFECTIVE ASSAYS TO SUBGROUP ATRT IN THE DAILY ROUTINE
por: Lobon-Iglesias, María-Jesús, et al.
Publicado: (2020)

ROMA: Representation and Quantification of Module Activity from Target Expression Data
por: Martignetti, Loredana, et al.
Publicado: (2016)

Kinesin KIFC1 actively transports bare double-stranded DNA
por: Farina, Francesca, et al.
Publicado: (2013)

Moesin Is a Major Regulator of Centrosome Behavior in Epithelial Cells with Extra Centrosomes
por: Sabino, Dora, et al.
Publicado: (2015)

Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis
por: Singh, Meetali, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jq2e1plptmrgt9tcq2mt0jhi9t