Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospectiv...

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Detalles Bibliográficos
Autores principales: Willeit, Peter, Bernar, Benoît, Zurl, Christoph, Al-Rawi, Mariam, Berghold, Andrea, Bernhard, David, Borena, Wegene, Doppler, Christian, Kerbl, Reinhold, Köhler, Alwin, Krause, Robert, Lamprecht, Bernd, Pröll, Johannes, Schmidt, Hannes, Steinmetz, Ivo, Stelzl, Evelyn, Stoiber, Heribert, von Laer, Dorothee, Zuber, Johannes, Müller, Thomas, Strenger, Volker, Wagner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393891/
https://www.ncbi.nlm.nih.gov/pubmed/34448449
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797
Descripción
Sumario:This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and non-infected individuals mainly tested negative (very high specificity).

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