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Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021

This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospectiv...

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Autores principales: Willeit, Peter, Bernar, Benoît, Zurl, Christoph, Al-Rawi, Mariam, Berghold, Andrea, Bernhard, David, Borena, Wegene, Doppler, Christian, Kerbl, Reinhold, Köhler, Alwin, Krause, Robert, Lamprecht, Bernd, Pröll, Johannes, Schmidt, Hannes, Steinmetz, Ivo, Stelzl, Evelyn, Stoiber, Heribert, von Laer, Dorothee, Zuber, Johannes, Müller, Thomas, Strenger, Volker, Wagner, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393891/
https://www.ncbi.nlm.nih.gov/pubmed/34448449
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797
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author Willeit, Peter
Bernar, Benoît
Zurl, Christoph
Al-Rawi, Mariam
Berghold, Andrea
Bernhard, David
Borena, Wegene
Doppler, Christian
Kerbl, Reinhold
Köhler, Alwin
Krause, Robert
Lamprecht, Bernd
Pröll, Johannes
Schmidt, Hannes
Steinmetz, Ivo
Stelzl, Evelyn
Stoiber, Heribert
von Laer, Dorothee
Zuber, Johannes
Müller, Thomas
Strenger, Volker
Wagner, Michael
author_facet Willeit, Peter
Bernar, Benoît
Zurl, Christoph
Al-Rawi, Mariam
Berghold, Andrea
Bernhard, David
Borena, Wegene
Doppler, Christian
Kerbl, Reinhold
Köhler, Alwin
Krause, Robert
Lamprecht, Bernd
Pröll, Johannes
Schmidt, Hannes
Steinmetz, Ivo
Stelzl, Evelyn
Stoiber, Heribert
von Laer, Dorothee
Zuber, Johannes
Müller, Thomas
Strenger, Volker
Wagner, Michael
author_sort Willeit, Peter
collection PubMed
description This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and non-infected individuals mainly tested negative (very high specificity).
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spelling pubmed-83938912021-09-03 Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 Willeit, Peter Bernar, Benoît Zurl, Christoph Al-Rawi, Mariam Berghold, Andrea Bernhard, David Borena, Wegene Doppler, Christian Kerbl, Reinhold Köhler, Alwin Krause, Robert Lamprecht, Bernd Pröll, Johannes Schmidt, Hannes Steinmetz, Ivo Stelzl, Evelyn Stoiber, Heribert von Laer, Dorothee Zuber, Johannes Müller, Thomas Strenger, Volker Wagner, Michael Euro Surveill Rapid Communication This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and non-infected individuals mainly tested negative (very high specificity). European Centre for Disease Prevention and Control (ECDC) 2021-08-26 /pmc/articles/PMC8393891/ /pubmed/34448449 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Willeit, Peter
Bernar, Benoît
Zurl, Christoph
Al-Rawi, Mariam
Berghold, Andrea
Bernhard, David
Borena, Wegene
Doppler, Christian
Kerbl, Reinhold
Köhler, Alwin
Krause, Robert
Lamprecht, Bernd
Pröll, Johannes
Schmidt, Hannes
Steinmetz, Ivo
Stelzl, Evelyn
Stoiber, Heribert
von Laer, Dorothee
Zuber, Johannes
Müller, Thomas
Strenger, Volker
Wagner, Michael
Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021
title Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021
title_full Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021
title_fullStr Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021
title_full_unstemmed Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021
title_short Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021
title_sort sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting sars-cov-2 infection in schools, austria, march 2021
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393891/
https://www.ncbi.nlm.nih.gov/pubmed/34448449
http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797
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