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Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021
This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospectiv...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Centre for Disease Prevention and Control (ECDC)
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393891/ https://www.ncbi.nlm.nih.gov/pubmed/34448449 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797 |
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author | Willeit, Peter Bernar, Benoît Zurl, Christoph Al-Rawi, Mariam Berghold, Andrea Bernhard, David Borena, Wegene Doppler, Christian Kerbl, Reinhold Köhler, Alwin Krause, Robert Lamprecht, Bernd Pröll, Johannes Schmidt, Hannes Steinmetz, Ivo Stelzl, Evelyn Stoiber, Heribert von Laer, Dorothee Zuber, Johannes Müller, Thomas Strenger, Volker Wagner, Michael |
author_facet | Willeit, Peter Bernar, Benoît Zurl, Christoph Al-Rawi, Mariam Berghold, Andrea Bernhard, David Borena, Wegene Doppler, Christian Kerbl, Reinhold Köhler, Alwin Krause, Robert Lamprecht, Bernd Pröll, Johannes Schmidt, Hannes Steinmetz, Ivo Stelzl, Evelyn Stoiber, Heribert von Laer, Dorothee Zuber, Johannes Müller, Thomas Strenger, Volker Wagner, Michael |
author_sort | Willeit, Peter |
collection | PubMed |
description | This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and non-infected individuals mainly tested negative (very high specificity). |
format | Online Article Text |
id | pubmed-8393891 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | European Centre for Disease Prevention and Control (ECDC) |
record_format | MEDLINE/PubMed |
spelling | pubmed-83938912021-09-03 Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 Willeit, Peter Bernar, Benoît Zurl, Christoph Al-Rawi, Mariam Berghold, Andrea Bernhard, David Borena, Wegene Doppler, Christian Kerbl, Reinhold Köhler, Alwin Krause, Robert Lamprecht, Bernd Pröll, Johannes Schmidt, Hannes Steinmetz, Ivo Stelzl, Evelyn Stoiber, Heribert von Laer, Dorothee Zuber, Johannes Müller, Thomas Strenger, Volker Wagner, Michael Euro Surveill Rapid Communication This study evaluates the performance of the antigen-based anterior nasal screening programme implemented in all Austrian schools to detect SARS-CoV-2 infections. We combined nationwide antigen-based screening data obtained in March 2021 from 5,370 schools (Grade 1–8) with an RT-qPCR-based prospective cohort study comprising a representative sample of 244 schools. Considering a range of assumptions, only a subset of infected individuals are detected with the programme (low to moderate sensitivity) and non-infected individuals mainly tested negative (very high specificity). European Centre for Disease Prevention and Control (ECDC) 2021-08-26 /pmc/articles/PMC8393891/ /pubmed/34448449 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797 Text en This article is copyright of the authors or their affiliated institutions, 2021. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made. |
spellingShingle | Rapid Communication Willeit, Peter Bernar, Benoît Zurl, Christoph Al-Rawi, Mariam Berghold, Andrea Bernhard, David Borena, Wegene Doppler, Christian Kerbl, Reinhold Köhler, Alwin Krause, Robert Lamprecht, Bernd Pröll, Johannes Schmidt, Hannes Steinmetz, Ivo Stelzl, Evelyn Stoiber, Heribert von Laer, Dorothee Zuber, Johannes Müller, Thomas Strenger, Volker Wagner, Michael Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 |
title | Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 |
title_full | Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 |
title_fullStr | Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 |
title_full_unstemmed | Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 |
title_short | Sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting SARS-CoV-2 infection in schools, Austria, March 2021 |
title_sort | sensitivity and specificity of the antigen-based anterior nasal self-testing programme for detecting sars-cov-2 infection in schools, austria, march 2021 |
topic | Rapid Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393891/ https://www.ncbi.nlm.nih.gov/pubmed/34448449 http://dx.doi.org/10.2807/1560-7917.ES.2021.26.34.2100797 |
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