Cargando…
Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China
Hypertension is one of the most common chronic diseases and a major risk factor for stroke, myocardial infarction and cardiovascular death. Cognitive frailty is an important predictor of all-cause mortality and dementia in aging individuals. Hypertension is closely related to cognitive frailty and t...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393928/ https://www.ncbi.nlm.nih.gov/pubmed/34439637 http://dx.doi.org/10.3390/brainsci11081018 |
_version_ | 1783743835591933952 |
---|---|
author | Wang, Can Zhang, Jiechun Hu, Chengping Wang, Yanbo |
author_facet | Wang, Can Zhang, Jiechun Hu, Chengping Wang, Yanbo |
author_sort | Wang, Can |
collection | PubMed |
description | Hypertension is one of the most common chronic diseases and a major risk factor for stroke, myocardial infarction and cardiovascular death. Cognitive frailty is an important predictor of all-cause mortality and dementia in aging individuals. Hypertension is closely related to cognitive frailty and these two conditions often coexist in aging individuals. Few studies have explored the relationship between hypertension and cognitive frailty in the Chinese population. This study investigates the epidemiological characteristics of and factors related to cognitive frailty in aging Chinese patients with hypertension. In total, cognitive function, weakness, social support, depression and sociodemographic were assessed in 305 participants aged 60 and over. Univariate and multivariate logistic regression models were constructed. The prevalence of cognitive frailty in aging Chinese hypertensive patients was 9.8% (95% CI = 6.4–13.2%). After adjusting for confounding variables, logistic regression showed that the course of hypertension (6–10 years, OR = 8.588, 95% CI = 1.608–45.859;course of more than 10 years, OR = 9.020, 95%CI = 1.854–43.892), multimorbidity (OR = 11.231, 95% CI = 2.912–43.322), depression (OR = 6.917, 95% CI = 2.424–19.738) and social support (OR = 0.187, 95% CI = 0.071–0.492) were independently associated with cognitive frailty. The prevalence of cognitive frailty in aging patients with hypertension in China should not be ignored. The course of hypertension, multimorbidity and depression are the risk factors of cognitive frailty in the aging population and a better level of social support is the protective factor for cognitive frailty. |
format | Online Article Text |
id | pubmed-8393928 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83939282021-08-28 Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China Wang, Can Zhang, Jiechun Hu, Chengping Wang, Yanbo Brain Sci Article Hypertension is one of the most common chronic diseases and a major risk factor for stroke, myocardial infarction and cardiovascular death. Cognitive frailty is an important predictor of all-cause mortality and dementia in aging individuals. Hypertension is closely related to cognitive frailty and these two conditions often coexist in aging individuals. Few studies have explored the relationship between hypertension and cognitive frailty in the Chinese population. This study investigates the epidemiological characteristics of and factors related to cognitive frailty in aging Chinese patients with hypertension. In total, cognitive function, weakness, social support, depression and sociodemographic were assessed in 305 participants aged 60 and over. Univariate and multivariate logistic regression models were constructed. The prevalence of cognitive frailty in aging Chinese hypertensive patients was 9.8% (95% CI = 6.4–13.2%). After adjusting for confounding variables, logistic regression showed that the course of hypertension (6–10 years, OR = 8.588, 95% CI = 1.608–45.859;course of more than 10 years, OR = 9.020, 95%CI = 1.854–43.892), multimorbidity (OR = 11.231, 95% CI = 2.912–43.322), depression (OR = 6.917, 95% CI = 2.424–19.738) and social support (OR = 0.187, 95% CI = 0.071–0.492) were independently associated with cognitive frailty. The prevalence of cognitive frailty in aging patients with hypertension in China should not be ignored. The course of hypertension, multimorbidity and depression are the risk factors of cognitive frailty in the aging population and a better level of social support is the protective factor for cognitive frailty. MDPI 2021-07-30 /pmc/articles/PMC8393928/ /pubmed/34439637 http://dx.doi.org/10.3390/brainsci11081018 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Wang, Can Zhang, Jiechun Hu, Chengping Wang, Yanbo Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China |
title | Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China |
title_full | Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China |
title_fullStr | Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China |
title_full_unstemmed | Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China |
title_short | Prevalence and Risk Factors for Cognitive Frailty in Aging Hypertensive Patients in China |
title_sort | prevalence and risk factors for cognitive frailty in aging hypertensive patients in china |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8393928/ https://www.ncbi.nlm.nih.gov/pubmed/34439637 http://dx.doi.org/10.3390/brainsci11081018 |
work_keys_str_mv | AT wangcan prevalenceandriskfactorsforcognitivefrailtyinaginghypertensivepatientsinchina AT zhangjiechun prevalenceandriskfactorsforcognitivefrailtyinaginghypertensivepatientsinchina AT huchengping prevalenceandriskfactorsforcognitivefrailtyinaginghypertensivepatientsinchina AT wangyanbo prevalenceandriskfactorsforcognitivefrailtyinaginghypertensivepatientsinchina |