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Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation

Atrial fibrillation (AF) recurrence after radiofrequency catheter ablation (RFCA) remains a challenging issue. This study aims to explore the left atrial appendage function by transesophageal echocardiography (TEE) and assess its value in predicting AF recurrence following RFCA in paroxysmal AF pati...

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Autores principales: Istratoaie, Sabina, Vesa, Ștefan C., Cismaru, Gabriel, Pop, Dana, Roșu, Radu, Puiu, Mihai, Pepine, Diana, Ciobanu, Cristina, Minciuna, Ioan A., Simu, Gelu, Zdrenghea, Dumitru, Buzoianu, Anca D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394000/
https://www.ncbi.nlm.nih.gov/pubmed/34441399
http://dx.doi.org/10.3390/diagnostics11081465
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author Istratoaie, Sabina
Vesa, Ștefan C.
Cismaru, Gabriel
Pop, Dana
Roșu, Radu
Puiu, Mihai
Pepine, Diana
Ciobanu, Cristina
Minciuna, Ioan A.
Simu, Gelu
Zdrenghea, Dumitru
Buzoianu, Anca D.
author_facet Istratoaie, Sabina
Vesa, Ștefan C.
Cismaru, Gabriel
Pop, Dana
Roșu, Radu
Puiu, Mihai
Pepine, Diana
Ciobanu, Cristina
Minciuna, Ioan A.
Simu, Gelu
Zdrenghea, Dumitru
Buzoianu, Anca D.
author_sort Istratoaie, Sabina
collection PubMed
description Atrial fibrillation (AF) recurrence after radiofrequency catheter ablation (RFCA) remains a challenging issue. This study aims to explore the left atrial appendage function by transesophageal echocardiography (TEE) and assess its value in predicting AF recurrence following RFCA in paroxysmal AF patients. Eighty-one patients with paroxysmal AF that underwent RFCA were recruited. TEE was performed before ablation with the assessment of left atrial appendage emptying flow velocity (LAAeV). AF recurrence occurred in 24 patients (29.6%) within 12 months after RFCA. The left atrium diameter (LAD) and left atrium volume index (LAVI) were both significantly higher in the recurrence group compared to the non-recurrence group, while the LAAeV was significantly lower in the recurrence group. LAD, LAVi and LAAeV were univariately significant risk factors for AF recurrence after ablation. Based on receiver operating curve (ROC), LAAeV < 40.5 cm/s, LAVi > 40.5 mL and LAD > 41 mm were identified as cut-off values for predicting AF recurrence. In multivariate regression analysis LAAeV < 40.5 cm/s (HR 8.194, 95% CI 2.980–22.530, p < 0.001) was identified as the only statistically significant independent predictor of AF recurrence, as the statistical significance threshold was not achieved for LAVI > 40.5 mL and LAD > 41 mm (p = 0.319; p = 0.507, respectively). A low LAAeV was the only important independent predictor of AF recurrence within 1 year after first RFCA.
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spelling pubmed-83940002021-08-28 Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation Istratoaie, Sabina Vesa, Ștefan C. Cismaru, Gabriel Pop, Dana Roșu, Radu Puiu, Mihai Pepine, Diana Ciobanu, Cristina Minciuna, Ioan A. Simu, Gelu Zdrenghea, Dumitru Buzoianu, Anca D. Diagnostics (Basel) Article Atrial fibrillation (AF) recurrence after radiofrequency catheter ablation (RFCA) remains a challenging issue. This study aims to explore the left atrial appendage function by transesophageal echocardiography (TEE) and assess its value in predicting AF recurrence following RFCA in paroxysmal AF patients. Eighty-one patients with paroxysmal AF that underwent RFCA were recruited. TEE was performed before ablation with the assessment of left atrial appendage emptying flow velocity (LAAeV). AF recurrence occurred in 24 patients (29.6%) within 12 months after RFCA. The left atrium diameter (LAD) and left atrium volume index (LAVI) were both significantly higher in the recurrence group compared to the non-recurrence group, while the LAAeV was significantly lower in the recurrence group. LAD, LAVi and LAAeV were univariately significant risk factors for AF recurrence after ablation. Based on receiver operating curve (ROC), LAAeV < 40.5 cm/s, LAVi > 40.5 mL and LAD > 41 mm were identified as cut-off values for predicting AF recurrence. In multivariate regression analysis LAAeV < 40.5 cm/s (HR 8.194, 95% CI 2.980–22.530, p < 0.001) was identified as the only statistically significant independent predictor of AF recurrence, as the statistical significance threshold was not achieved for LAVI > 40.5 mL and LAD > 41 mm (p = 0.319; p = 0.507, respectively). A low LAAeV was the only important independent predictor of AF recurrence within 1 year after first RFCA. MDPI 2021-08-13 /pmc/articles/PMC8394000/ /pubmed/34441399 http://dx.doi.org/10.3390/diagnostics11081465 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Istratoaie, Sabina
Vesa, Ștefan C.
Cismaru, Gabriel
Pop, Dana
Roșu, Radu
Puiu, Mihai
Pepine, Diana
Ciobanu, Cristina
Minciuna, Ioan A.
Simu, Gelu
Zdrenghea, Dumitru
Buzoianu, Anca D.
Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
title Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
title_full Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
title_fullStr Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
title_full_unstemmed Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
title_short Value of Left Atrial Appendage Function Measured by Transesophageal Echocardiography for Prediction of Atrial Fibrillation Recurrence after Radiofrequency Catheter Ablation
title_sort value of left atrial appendage function measured by transesophageal echocardiography for prediction of atrial fibrillation recurrence after radiofrequency catheter ablation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394000/
https://www.ncbi.nlm.nih.gov/pubmed/34441399
http://dx.doi.org/10.3390/diagnostics11081465
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