Direct Endoplasmic Reticulum Targeting by the Selective Alkylphospholipid Analog and Antitumor Ether Lipid Edelfosine as a Therapeutic Approach in Pancreatic Cancer

SIMPLE SUMMARY: Pancreatic ductal adenocarcinoma (PDAC), comprising 90–95% of all pancreatic cancers, is one of the deadliest human cancers, with a gloomy prognosis and ~6-month median survival in metastatic tumors. Even patients with resectable tumors show a poor survival rate after surgery. Thus,...

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Detalles Bibliográficos
Autores principales: Mollinedo, Faustino, Gajate, Consuelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394177/
https://www.ncbi.nlm.nih.gov/pubmed/34439330
http://dx.doi.org/10.3390/cancers13164173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394177/
https://www.ncbi.nlm.nih.gov/pubmed/34439330
http://dx.doi.org/10.3390/cancers13164173

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