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Organization of DNA Replication Origin Firing in Xenopus Egg Extracts: The Role of Intra-S Checkpoint

During cell division, the duplication of the genome starts at multiple positions called replication origins. Origin firing requires the interaction of rate-limiting factors with potential origins during the S(ynthesis)-phase of the cell cycle. Origins fire as synchronous clusters which is proposed t...

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Detalles Bibliográficos
Autores principales: Ciardo, Diletta, Haccard, Olivier, Narassimprakash, Hemalatha, Arbona, Jean-Michel, Hyrien, Olivier, Audit, Benjamin, Marheineke, Kathrin, Goldar, Arach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394201/
https://www.ncbi.nlm.nih.gov/pubmed/34440398
http://dx.doi.org/10.3390/genes12081224