Conditional Knock out of High-Mobility Group Box 1 (HMGB1) in Rods Reduces Autophagy Activation after Retinal Detachment

After retinal detachment (RD), the induction of autophagy protects photoreceptors (PR) from apoptotic cell death. The cytoplasmic high-mobility group box 1 (HMGB1) promotes autophagy. We previously demonstrated that the deletion of HMGB1 from rod PRs results in a more rapid death of these cells afte...

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Detalles Bibliográficos
Autores principales: Ross, Bing X., Jia, Lin, Kong, Dejuan, Wang, Tiantian, Hager, Heather M., Abcouwer, Steven F., Zacks, David N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394251/
https://www.ncbi.nlm.nih.gov/pubmed/34440779
http://dx.doi.org/10.3390/cells10082010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394251/
https://www.ncbi.nlm.nih.gov/pubmed/34440779
http://dx.doi.org/10.3390/cells10082010

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