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Conditional Knock out of High-Mobility Group Box 1 (HMGB1) in Rods Reduces Autophagy Activation after Retinal Detachment

After retinal detachment (RD), the induction of autophagy protects photoreceptors (PR) from apoptotic cell death. The cytoplasmic high-mobility group box 1 (HMGB1) promotes autophagy. We previously demonstrated that the deletion of HMGB1 from rod PRs results in a more rapid death of these cells afte...

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Detalles Bibliográficos
Autores principales:	Ross, Bing X., Jia, Lin, Kong, Dejuan, Wang, Tiantian, Hager, Heather M., Abcouwer, Steven F., Zacks, David N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394251/ https://www.ncbi.nlm.nih.gov/pubmed/34440779 http://dx.doi.org/10.3390/cells10082010

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