Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice

Acetaminophen (APA)-induced hepatotoxicity is coupled with the activation of autophagy. We sought to determine whether selective autophagy of the endoplasmic reticulum (ER), termed ER-phagy, is involved in APA hepatotoxicity and to explore its potential as a therapeutic target for APA-induced liver...

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Detalles Bibliográficos
Autores principales: Yan, Mingzhu, Wang, Zhi, Xia, Tianji, Jin, Suwei, Liu, Yongguang, Hu, Hongbo, Chang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394328/
https://www.ncbi.nlm.nih.gov/pubmed/34440143
http://dx.doi.org/10.3390/biomedicines9080939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394328/
https://www.ncbi.nlm.nih.gov/pubmed/34440143
http://dx.doi.org/10.3390/biomedicines9080939

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