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Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice
Acetaminophen (APA)-induced hepatotoxicity is coupled with the activation of autophagy. We sought to determine whether selective autophagy of the endoplasmic reticulum (ER), termed ER-phagy, is involved in APA hepatotoxicity and to explore its potential as a therapeutic target for APA-induced liver...
Autores principales: | Yan, Mingzhu, Wang, Zhi, Xia, Tianji, Jin, Suwei, Liu, Yongguang, Hu, Hongbo, Chang, Qi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394328/ https://www.ncbi.nlm.nih.gov/pubmed/34440143 http://dx.doi.org/10.3390/biomedicines9080939 |
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