Cargando…

Enhancement of TEX264-Mediated ER-Phagy Contributes to the Therapeutic Effect of Glycycoumarin against APA Hepatotoxicity in Mice

Acetaminophen (APA)-induced hepatotoxicity is coupled with the activation of autophagy. We sought to determine whether selective autophagy of the endoplasmic reticulum (ER), termed ER-phagy, is involved in APA hepatotoxicity and to explore its potential as a therapeutic target for APA-induced liver...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yan, Mingzhu, Wang, Zhi, Xia, Tianji, Jin, Suwei, Liu, Yongguang, Hu, Hongbo, Chang, Qi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394328/ https://www.ncbi.nlm.nih.gov/pubmed/34440143 http://dx.doi.org/10.3390/biomedicines9080939

Ejemplares similares

Eat it right: ER-phagy and recovER-phagy
por: Loi, Marisa, et al.
Publicado: (2018)

Pharmacological Activities and Pharmacokinetics of Glycycoumarin
por: Tang, Yumei, et al.
Publicado: (2022)

ER remodeling via ER-phagy
por: Gubas, Andrea, et al.
Publicado: (2022)

Mechanistic insights in recov-ER-phagy: micro-ER-phagy to recover from stress
por: Loi, Marisa, et al.
Publicado: (2020)

The various shades of ER‐phagy
por: Stolz, Alexandra, et al.
Publicado: (2019)

ER-Phagy and Microbial Infection
por: Li, Jiahui, et al.
Publicado: (2021)

Glycycoumarin inhibits hepatocyte lipoapoptosis through activation of autophagy and inhibition of ER stress/GSK-3-mediated mitochondrial pathway
por: Zhang, Enxiang, et al.
Publicado: (2016)

ER-phagy in the Occurrence and Development of Cancer
por: Zhou, Huimin, et al.
Publicado: (2022)

ER-Phagy and ER Stress Response (ERSR) in Plants
por: Zeng, Yonglun, et al.
Publicado: (2019)

ER-Phagy and Its Role in ER Homeostasis in Plants
por: Bao, Yan, et al.
Publicado: (2020)

ER-Phagy: A New Regulator of ER Homeostasis
por: Yang, Ming, et al.
Publicado: (2021)

A Role for Macro-ER-Phagy in ER Quality Control
por: Lipatova, Zhanna, et al.
Publicado: (2015)

Advances in ER-Phagy and Its Diseases Relevance
por: He, Lingang, et al.
Publicado: (2021)

Choline kinase inhibition promotes ER-phagy
por: Tavasoli, Mahtab, et al.
Publicado: (2022)

ER‐phagy: selective autophagy of the endoplasmic reticulum
por: Mochida, Keisuke, et al.
Publicado: (2022)

Cajaninstilbene Acid Ameliorates Acetaminophen-Induced Liver Injury Through Enhancing Sestrin2/AMPK-Mediated Mitochondrial Quality Control
por: Yan, Mingzhu, et al.
Publicado: (2022)

Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy
por: Foronda, Hector, et al.
Publicado: (2023)

FAM134B-mediated ER-phagy regulates ER-mitochondria interaction through MAMs: FAM134B-mediated ER-phagy regulates ER-mitochondria interaction
por: Chen, Wei, et al.
Publicado: (2021)

ER‐phagy: shaping up and destressing the endoplasmic reticulum
por: Wilkinson, Simon
Publicado: (2019)

Reticulon Homology Domain-Containing Proteins and ER-Phagy
por: D’Eletto, Manuela, et al.
Publicado: (2020)

Characterization of constitutive ER-phagy of excess membrane proteins
por: Lipatova, Zhanna, et al.
Publicado: (2020)

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum
por: González, Alexis, et al.
Publicado: (2023)

ER stress as a trigger of UPR and ER-phagy in cancer growth and spread
por: Cherubini, Alessandro, et al.
Publicado: (2022)

ER-phagy requires the assembly of actin at sites of contact between the cortical ER and endocytic pits
por: Liu, Dongmei, et al.
Publicado: (2022)

Regulation of ER-phagy by a Ypt/Rab GTPase module
por: Lipatova, Zhanna, et al.
Publicado: (2013)

Critical roles of FAM134B in ER-phagy and diseases
por: Mo, Jie, et al.
Publicado: (2020)

Open questions: why should we care about ER-phagy and ER remodelling?
por: Dikic, Ivan
Publicado: (2018)

Palmitate reduces starvation-induced ER stress by inhibiting ER-phagy in hypothalamic cells
por: Lim, Yun, et al.
Publicado: (2021)

Glycycoumarin exerts anti-liver cancer activity by directly targeting T-LAK cell-originated protein kinase
por: Song, Xinhua, et al.
Publicado: (2016)

Repurposing Brigatinib for the Treatment of Colorectal Cancer Based on Inhibition of ER-phagy
por: Zhang, Zhe, et al.
Publicado: (2019)

CALCOCO1 acts with VAMP‐associated proteins to mediate ER‐phagy
por: Nthiga, Thaddaeus Mutugi, et al.
Publicado: (2020)

Eating the unknown: Xenophagy and ER-phagy are cytoprotective defenses against pathogens
por: Reggio, Alessio, et al.
Publicado: (2020)

Selective Autophagy of the Protein Homeostasis Machinery: Ribophagy, Proteaphagy and ER-Phagy
por: Beese, Carsten J., et al.
Publicado: (2020)

Glycycoumarin Sensitizes Liver Cancer Cells to ABT-737 by Targeting De Novo Lipogenesis and TOPK-Survivin Axis
por: Zhang, Enxiang, et al.
Publicado: (2018)

Endoplasmic reticulum turnover: ER-phagy and other flavors in selective and non-selective ER clearance
por: Fregno, Ilaria, et al.
Publicado: (2018)

ESCRT-III-driven piecemeal micro-ER-phagy remodels the ER during recovery from ER stress
por: Loi, Marisa, et al.
Publicado: (2019)

RETREG1-mediated ER-phagy activation induced by glucose deprivation alleviates nucleus pulposus cell damage via ER stress pathway: RETREG1-mediated ER-phagy modulates NP cell damage
por: Luo, Rongjin, et al.
Publicado: (2022)

ER-phagy: mechanisms, regulation, and diseases connected to the lysosomal clearance of the endoplasmic reticulum
por: Reggiori, Fulvio, et al.
Publicado: (2022)

Metabolic adaption of cancer cells toward autophagy: Is there a role for ER-phagy?
por: Gentile, Debora, et al.
Publicado: (2022)

Signal-Retaining Autophagy Indicator as a Quantitative Imaging Method for ER-Phagy
por: Jimenez-Moreno, Natalia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7k1bm0p1t19e8jfl6tksin85i7