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17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway

Apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE1/Ref-1) is a multifunctional protein that can be secreted, and recently suggested as new biomarker for vascular inflammation. However, the endogenous hormones for APE1/Ref-1 secretion and its underlying mechanisms are not defined. Here, the ef...

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Detalles Bibliográficos
Autores principales:	Lee, Yu-Ran, Joo, Hee-Kyoung, Lee, Eun-Ok, Kim, Sungmin, Jin, Hao, Choi, Yeon-Hee, Kim, Cuk-Seong, Jeon, Byeong-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394342/ https://www.ncbi.nlm.nih.gov/pubmed/34440244 http://dx.doi.org/10.3390/biomedicines9081040

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