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Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management
Acute Ischemic Stroke (AIS) in children is an acute neurologic emergency associated with significant morbidity and mortality. Although the incidence of AIS in pediatric patients is considerably lower than in adults, the overall cumulative negative impact of the quality of life could be even higher i...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394345/ https://www.ncbi.nlm.nih.gov/pubmed/34438540 http://dx.doi.org/10.3390/children8080649 |
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author | Klučka, Jozef Klabusayová, Eva Musilová, Tereza Kramplová, Tereza Skříšovská, Tamara Kratochvíl, Milan Kosinová, Martina Horák, Ondřej Ošlejšková, Hana Jabandžiev, Petr Štourač, Petr |
author_facet | Klučka, Jozef Klabusayová, Eva Musilová, Tereza Kramplová, Tereza Skříšovská, Tamara Kratochvíl, Milan Kosinová, Martina Horák, Ondřej Ošlejšková, Hana Jabandžiev, Petr Štourač, Petr |
author_sort | Klučka, Jozef |
collection | PubMed |
description | Acute Ischemic Stroke (AIS) in children is an acute neurologic emergency associated with significant morbidity and mortality. Although the incidence of AIS in pediatric patients is considerably lower than in adults, the overall cumulative negative impact of the quality of life could be even higher in children. The age-related variable clinical presentation could result in a delay in diagnosis and could negatively influence the overall outcome. The early management should be based on early recognition, acute transfer to pediatric AIS centre, standardised approach (ABCDE), early neurologic examination together with neuroimaging (preferable Magnetic Resonance Imaging—MRI). The treatment is based on supportive therapy (normoxemia, normocapnia, normotension and normoglycemia) in combination with intravenous/intraarterial thrombolytic therapy and/or mechanical thrombectomy in selected cases. Pediatric stroke centres, together with the implementation of local stroke management protocols, could further improve the outcome of pediatric patients with AIS. |
format | Online Article Text |
id | pubmed-8394345 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-83943452021-08-28 Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management Klučka, Jozef Klabusayová, Eva Musilová, Tereza Kramplová, Tereza Skříšovská, Tamara Kratochvíl, Milan Kosinová, Martina Horák, Ondřej Ošlejšková, Hana Jabandžiev, Petr Štourač, Petr Children (Basel) Review Acute Ischemic Stroke (AIS) in children is an acute neurologic emergency associated with significant morbidity and mortality. Although the incidence of AIS in pediatric patients is considerably lower than in adults, the overall cumulative negative impact of the quality of life could be even higher in children. The age-related variable clinical presentation could result in a delay in diagnosis and could negatively influence the overall outcome. The early management should be based on early recognition, acute transfer to pediatric AIS centre, standardised approach (ABCDE), early neurologic examination together with neuroimaging (preferable Magnetic Resonance Imaging—MRI). The treatment is based on supportive therapy (normoxemia, normocapnia, normotension and normoglycemia) in combination with intravenous/intraarterial thrombolytic therapy and/or mechanical thrombectomy in selected cases. Pediatric stroke centres, together with the implementation of local stroke management protocols, could further improve the outcome of pediatric patients with AIS. MDPI 2021-07-28 /pmc/articles/PMC8394345/ /pubmed/34438540 http://dx.doi.org/10.3390/children8080649 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Klučka, Jozef Klabusayová, Eva Musilová, Tereza Kramplová, Tereza Skříšovská, Tamara Kratochvíl, Milan Kosinová, Martina Horák, Ondřej Ošlejšková, Hana Jabandžiev, Petr Štourač, Petr Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management |
title | Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management |
title_full | Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management |
title_fullStr | Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management |
title_full_unstemmed | Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management |
title_short | Pediatric Patient with Ischemic Stroke: Initial Approach and Early Management |
title_sort | pediatric patient with ischemic stroke: initial approach and early management |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394345/ https://www.ncbi.nlm.nih.gov/pubmed/34438540 http://dx.doi.org/10.3390/children8080649 |
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