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New Insights into Xenotransplantation for Cartilage Repair: Porcine Multi-Genetically Modified Chondrocytes as a Promising Cell Source

Transplantation of xenogenic porcine chondrocytes could represent a future strategy for the treatment of human articular cartilage defects. Major obstacles are humoral and cellular rejection processes triggered by xenogenic epitopes like α-1,3-Gal and Neu5Gc. Besides knockout (KO) of genes responsib...

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Detalles Bibliográficos
Autores principales:	Tritschler, Hanna, Fischer, Konrad, Seissler, Jochen, Fiedler, Jörg, Halbgebauer, Rebecca, Huber-Lang, Markus, Schnieke, Angelika, Brenner, Rolf E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394410/ https://www.ncbi.nlm.nih.gov/pubmed/34440921 http://dx.doi.org/10.3390/cells10082152

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