Cargando…

The Neuroprotective Effect of L-Carnitine against Glyceraldehyde-Induced Metabolic Impairment: Possible Implications in Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive regression and memory loss. Dysfunctions of both glucose metabolism and mitochondrial dynamics have been recognized as the main upstream events of the degenerative processes leading to AD. It has been rec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Magi, Simona, Preziuso, Alessandra, Piccirillo, Silvia, Giampieri, Francesca, Cianciosi, Danila, Orciani, Monia, Amoroso, Salvatore
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8394427/ https://www.ncbi.nlm.nih.gov/pubmed/34440878 http://dx.doi.org/10.3390/cells10082109

Ejemplares similares

Exploring the Role of NCX1 and NCX3 in an In Vitro Model of Metabolism Impairment: Potential Neuroprotective Targets for Alzheimer’s Disease
por: Preziuso, Alessandra, et al.
Publicado: (2023)

The Hidden Notes of Redox Balance in Neurodegenerative Diseases
por: Piccirillo, Silvia, et al.
Publicado: (2022)

Gateways for Glutamate Neuroprotection in Parkinson’s Disease (PD): Essential Role of EAAT3 and NCX1 Revealed in an In Vitro Model of PD
por: Piccirillo, Silvia, et al.
Publicado: (2020)

A new K(+)channel-independent mechanism is involved in the antioxidant effect of XE-991 in an in vitro model of glucose metabolism impairment: implications for Alzheimer’s disease
por: Piccirillo, Silvia, et al.
Publicado: (2022)

Excitatory Amino Acid Transporters (EAATs): Glutamate Transport and Beyond
por: Magi, Simona, et al.
Publicado: (2019)

Glutamate as a potential “survival factor” in an in vitro model of neuronal hypoxia/reoxygenation injury: leading role of the Na(+)/Ca(2+) exchanger
por: Piccirillo, Silvia, et al.
Publicado: (2018)

Essential role of the Na(+)-Ca2(+) exchanger (NCX) in glutamate-enhanced cell survival in cardiac cells exposed to hypoxia/reoxygenation
por: Maiolino, Marta, et al.
Publicado: (2017)

Possible Neuroprotective Effects of l-Carnitine on White-Matter Microstructural Damage and Cognitive Decline in Hemodialysis Patients
por: Ueno, Yuji, et al.
Publicado: (2021)

Selective inhibition of mitochondrial sodium-calcium exchanger protects striatal neurons from α-synuclein plus rotenone induced toxicity
por: Bastioli, Guendalina, et al.
Publicado: (2019)

Neuroprotective Effects of Pre-Treament with l-Carnitine and Acetyl-l-Carnitine on Ischemic Injury In Vivo and In Vitro
por: Zhang, Rui, et al.
Publicado: (2012)

Intracellular Calcium Dysregulation: Implications for Alzheimer's Disease
por: Magi, Simona, et al.
Publicado: (2016)

Autism and carnitine: A possible link
por: Demarquoy, Caroline, et al.
Publicado: (2019)

miRNAs, Mesenchymal Stromal Cells and Major Neoplastic and Inflammatory Skin Diseases: A Page Being Written: A Systematic Review
por: Di Vincenzo, Mariangela, et al.
Publicado: (2023)

Characterization and possible function of glyceraldehyde-3-phosphate dehydrogenase-spermatogenic protein GAPDHS in mammalian sperm
por: Margaryan, Hasmik, et al.
Publicado: (2015)

Neuroendocrine Effects of Carnitines on Reproductive Impairments
por: Petrillo, Tabatha, et al.
Publicado: (2021)

Bee Products: An Emblematic Example of Underutilized Sources of Bioactive Compounds
por: Giampieri, Francesca, et al.
Publicado: (2022)

Mesenchymal Stem Cells Profile in Adult Atopic Dermatitis and Effect of IL4-IL13 Inflammatory Pathway Inhibition In Vivo: Prospective Case-Control Study
por: Campanati, Anna, et al.
Publicado: (2022)

Low availability of carnitine precursors as a possible reason for the diminished plasma carnitine concentrations in pregnant women
por: Ringseis, Robert, et al.
Publicado: (2010)

Potential Health Benefit of Garlic Based on Human Intervention Studies: A Brief Overview
por: Ansary, Johura, et al.
Publicado: (2020)

Special Issue “The Role of Mesenchymal Stem Cells on Inflammatory and Fibrotic Diseases”
por: Di Vincenzo, Mariangela, et al.
Publicado: (2023)

Prebiotic access to enantioenriched glyceraldehyde mediated by peptides
por: Yu, Jinhan, et al.
Publicado: (2021)

Strawberry-Based Cosmetic Formulations Protect Human Dermal Fibroblasts against UVA-Induced Damage
por: Gasparrini, Massimiliano, et al.
Publicado: (2017)

The Influence of In Vitro Gastrointestinal Digestion on the Anticancer Activity of Manuka Honey
por: Cianciosi, Danila, et al.
Publicado: (2020)

THE HISTOCHEMICAL DEMONSTRATION OF GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE ACTIVITY
por: Himmelhoch, S. Ralph, et al.
Publicado: (1961)

A Possible Cause for the Differential Expression of a Subset of miRNAs in Mesenchymal Stem Cells Derived from Myometrium and Leiomyoma
por: Di Vincenzo, Mariangela, et al.
Publicado: (2022)

Preventive Role of L-Carnitine and Balanced Diet in Alzheimer’s Disease
por: Kepka, Alina, et al.
Publicado: (2020)

Neuroprotective effects of L-carnitine against oxygen-glucose deprivation in rat primary cortical neurons
por: Kim, Yu Jin, et al.
Publicado: (2012)

Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies
por: Šimić, Goran, et al.
Publicado: (2016)

THE INHIBITION OF d-GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE BY SPECIFIC ANTISERUM
por: Krebs, Edwin G., et al.
Publicado: (1948)

Testis-specific glyceraldehyde-3-phosphate dehydrogenase: origin and evolution
por: Kuravsky, Mikhail L, et al.
Publicado: (2011)

Functional consequences of piceatannol binding to glyceraldehyde-3-phosphate dehydrogenase
por: Gerszon, Joanna, et al.
Publicado: (2018)

Glyceraldehyde-3-phosphate Dehydrogenase Is a Multifaceted Therapeutic Target
por: Lazarev, Vladimir F., et al.
Publicado: (2020)

Glyceraldehyde as an Efficient Chemical Crosslinker Agent for the Formation of Chitosan Hydrogels
por: Carmona, Pierre, et al.
Publicado: (2021)

Treatment with acetyl-L-carnitine exerts a neuroprotective effect in the sciatic nerve following loose ligation: a functional and microanatomical study
por: Tomassoni, Daniele, et al.
Publicado: (2018)

TKTL1 Knockdown Impairs Hypoxia-Induced Glucose-6-phosphate Dehydrogenase and Glyceraldehyde-3-phosphate Dehydrogenase Overexpression
por: Baptista, Inês, et al.
Publicado: (2022)

Glyceraldehyde caused Alzheimer’s disease-like alterations in diagnostic marker levels in SH-SY5Y human neuroblastoma cells
por: Koriyama, Yoshiki, et al.
Publicado: (2015)

Strawberry (cv. Romina) Methanolic Extract and Anthocyanin-Enriched Fraction Improve Lipid Profile and Antioxidant Status in HepG2 Cells
por: Forbes-Hernández, Tamara Y., et al.
Publicado: (2017)

Nutrition and Rheumatoid Arthritis in the ‘Omics’ Era
por: Cassotta, Manuela, et al.
Publicado: (2021)

The Application of Digital Technologies and Artificial Intelligence in Healthcare: An Overview on Nutrition Assessment
por: Salinari, Alessia, et al.
Publicado: (2023)

Sudden cardiac death: focus on the genetics of channelopathies and cardiomyopathies
por: Magi, Simona, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_oe09adbts0h9ccd26t80eud3k8